Drug Interaction Report

Saquinavir may significantly increase the blood levels of elagolix. This can increase the risk and/or severity of side effects such as bone loss, depression, mood changes, suicidal thoughts, and liver problems. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. If both medications are necessary, it is generally recommended that the duration of concurrent use be limited to either 1 month or up to 6 months, depending on the dosage of elagolix you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food can enhance the levels of saquinavir in your body. Saquinavir should be taken with meals or within 2 hours after eating. This will make it easier for your body to absorb the medication. Grapefruit can raise the levels of saquinavir in your body. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.