Drug Interaction Report

Trimethoprim may increase the blood levels and effects of daprodustat. Contact your doctor if your condition changes or you experience increased side effects. Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or more frequent monitoring to safely use both medications. You should seek immediate medical attention if you develop sudden numbness, trouble seeing, loss of balance or coordination, lightheadedness, fainting, shortness of breath, or chest pain during treatment with daprodustat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Using daprodustat while smoking or drinking alcohol may increase the risk of side effects in the gastrointestinal tract such as stomach inflammation and bleeding. Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you have signs and symptoms of gastrointestinal bleeding such as abdominal pain, coughing up or vomiting fresh or dried blood that looks like coffee grounds, black, tarry stools, trouble swallowing, or chest or throat pain. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ask your doctor before using sulfamethoxazole together with ethanol (alcohol). Contact your doctor if you experience unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, or vomiting. If you experience these side effects, you may need to avoid ethanol (alcohol) while taking sulfamethoxazole. You should check your food and medicine labels to see if these products contain ethanol (alcohol). It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.