Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- nesiritide
- tolazoline
Interactions between your drugs
tolazoline nesiritide
Applies to: tolazoline, nesiritide
MONITOR: The coadministration of nesiritide with intravenous vasodilators such as nitroglycerin, nitroprusside, and milrinone has not been evaluated. Theoretically, an increase in symptomatic hypotension may occur due to possible additive pharmacodynamic effects in the vasculature. A similar risk may exist during coadministration with oral vasodilators such as hydralazine and minoxidil and other agents with vasodilating effects.
MANAGEMENT: Whether used alone or with other agents, nesiritide should be administered only in settings where blood pressure can be closely monitored. The dosage should be reduced or the drug discontinued in patients who develop hypotension.
References (1)
- (2022) "Product Information. Natrecor (nesiritide)." Scios Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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