Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- natalizumab
- peginterferon beta-1a
Interactions between your drugs
natalizumab peginterferon beta-1a
Applies to: natalizumab, peginterferon beta-1a
Ask your doctor before using peginterferon beta-1a together with natalizumab. Natalizumab increases the risk of a serious viral infection of the brain that can lead to disability or death. This risk is higher if you have a weak immune system or are receiving certain medications. Call your doctor at once if you develop any signs of infection such as fever, chills, sore throat, cough, stuffy nose, redness, pain, swelling, or painful urination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Immunomodulators for multiple sclerosis
Therapeutic duplication
The recommended maximum number of medicines in the 'immunomodulators for multiple sclerosis' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'immunomodulators for multiple sclerosis' category:
- natalizumab
- peginterferon beta-1a
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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