Drug Interaction Report

Vosoritide may cause transitory decreases in blood pressure and may have additive effects when used together with metoprolol. You may be more likely to experience side effects such as dizziness, weakness, headache, nausea, flushing or fainting. You may need frequent monitoring of your blood pressure to safely use both medications. To reduce the risk of low blood pressure and its associated symptoms, you should have adequate food intake before vosoritide administration and should drink approximately 8 to 10 ounces of liquids within the hour prior to vosoritide injection. Avoid driving or operating hazardous machinery until you know how these medications affect you and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food can enhance the levels of metoprolol in your body. You should take metoprolol at the same time each day, preferably with or immediately following meals. This will make it easier for your body to absorb the medication. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking metoprolol. Metoprolol is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Vosoritide may cause transient decreases in blood pressure. To reduce the risk of low blood pressure and its associated symptoms, you should have adequate food intake before vosoritide administration and should drink approximately 8 to 10 ounces of liquids within the hour prior to vosoritide injection. Tell your doctor if you experience fatigue, nausea, dizziness, or lightheadedness after vosoritide injection. Avoid driving or operating hazardous machinery until you know how this medication affects you and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Using metoprolol together with multivitamin with minerals may decrease the effects of metoprolol. Separate the administration times of metoprolol and multivitamin with minerals by at least 2 hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.