Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- itraconazole
- Nurtec ODT (rimegepant)
Interactions between your drugs
itraconazole rimegepant
Applies to: itraconazole, Nurtec ODT (rimegepant)
Itraconazole may significantly increase the blood levels of rimegepant. This may increase side effects such as nausea, indigestion, and abdominal pain or discomfort. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
itraconazole food
Applies to: itraconazole
Food increases the absorption of itraconazole capsules but decreases the absorption of itraconazole oral solution. Capsules should be taken immediately after a full meal and the solution be taken on an empty stomach to ensure best results.
rimegepant food
Applies to: Nurtec ODT (rimegepant)
If you are receiving therapy with rimegepant you may want to avoid the regular consumption of large amounts of grapefruits and grapefruit juice. Grapefruit can raise the levels of rimegepant in your body and lead to increased side effects. If grapefruit or grapefruit juice is consumed along with rimegepant, the manufacturer recommends avoiding a second dose of rimegepant within 48 hours. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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