Uptravi and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Uptravi (selexipag).
Selexipag Food
Minor Food Interaction
Food prolongs the gastrointestinal absorption of selexipag. When taken with food, the time to peak concentration (Tmax) was delayed and peak plasma concentration (Cmax) was approximately 30% lower. Selexipag systemic exposure (AUC) and that of its active metabolite did not significantly change, however. Selexipag may be taken with or without food. Tolerability may be improved when taken with food.
References (1)
- (2016) "Product Information. Uptravi (selexipag)." Actelion Pharmaceuticals US Inc
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Uptravi drug interactions
There are 240 drug interactions with Uptravi (selexipag).
Uptravi disease interactions
There are 2 disease interactions with Uptravi (selexipag) which include:
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- Drug class: agents for pulmonary hypertension
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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