Adempas and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with Adempas (riociguat).
Moderate Food Interaction
Chemical substances present in cigarette smoke may reduce the blood levels of riociguat. This means that the medication may be less effective if you smoke during treatment. Let your doctor know if you are a smoker, or if you start smoking or stop smoking during treatment with riociguat, because the dosage may need to be adjusted. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
riociguat - hypotension
Riociguat reduces blood pressure. There is a potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensive agents. Caution is advised when using riociguat in these patients.
- "Product Information. Adempas (riociguat)." Bayer Pharmaceutical Inc (2013):
Adempas drug interactions
There are 264 drug interactions with Adempas (riociguat).
Adempas disease interactions
There are 3 disease interactions with Adempas (riociguat) which include:
More about Adempas (riociguat)
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- FDA approval history
- Drug class: vasodilators
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Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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