Zosyn and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Zosyn (piperacillin / tazobactam).
Piperacillin High Blood Pressure (Hypertension)
Moderate Potential Hazard, High plausibility
piperacillin - sodium/potassium
Parenteral piperacillin sodium contains approximately 43 mg (1.85 mEq) of sodium per each gram of piperacillin activity. The combination, piperacillin-tazobactam, contains approximately 54 mg (2.35 mEq) of sodium per gram of piperacillin, or 108 mg (4.7 mEq) per 2.25 gram of total drug. The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention. In addition, hypokalemia has been reported rarely during therapy with piperacillin and other extended-spectrum penicillin antibiotics, which may be particularly important to bear in mind when treating patients with low potassium reserves or fluid and electrolyte imbalance. Clinical monitoring of electrolytes is recommended if these agents are used for prolonged periods.
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Zosyn drug interactions
There are 76 drug interactions with Zosyn (piperacillin / tazobactam).
Zosyn disease interactions
There are 8 disease interactions with Zosyn (piperacillin / tazobactam) which include:
- colitis
- coagulation abnormalities
- renal dysfunction
- renal dysfunction
- hemodialysis
- cystic fibrosis
- seizures
- sodium/potassium
More about Zosyn (piperacillin / tazobactam)
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- Drug class: penicillins/beta-lactamase inhibitors
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.