Xenleta and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Xenleta (lefamulin).
Lefamulin Food/Lifestyle
Moderate Food Interaction
The following interaction applies only if you are taking lefamulin (Xenleta) orally: Food may interfere with the absorption of lefamulin, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take lefamulin at least 1 hour before or 2 hours after a meal. It is best to avoid or limit the consumption of grapefruit and grapefruit juice during treatment with lefamulin, as it may increase blood levels of the medication and increase side effects. Talk to your doctor or pharmacist if you have any questions or concerns.
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Xenleta drug interactions
There are 565 drug interactions with Xenleta (lefamulin).
Xenleta disease interactions
There are 4 disease interactions with Xenleta (lefamulin) which include:
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- During pregnancy
- FDA approval history
- Drug class: miscellaneous antibiotics
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
