Skip to Content
Print Save

Xenleta (lefamulin) and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Xenleta (lefamulin):

Moderate

lefamulin food

Moderate Food Interaction

The following interaction applies only if you are taking lefamulin (Xenleta) orally: Food may interfere with the absorption of lefamulin, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take lefamulin at least 1 hour before or 2 hours after a meal. It is best to avoid or limit the consumption of grapefruit and grapefruit juice during treatment with lefamulin, as it may increase blood levels of the medication and increase side effects. Talk to your doctor or pharmacist if you have any questions or concerns.

Switch to professional interaction data

Xenleta (lefamulin) drug interactions

There are 546 drug interactions with Xenleta (lefamulin)

Xenleta (lefamulin) disease interactions

There are 4 disease interactions with Xenleta (lefamulin) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer