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Fludrocortisone and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with fludrocortisone.

Moderate

High Blood Pressure (Hypertension)

Moderate Potential Hazard, High plausibility

corticosteroids - fluid retention

Corticosteroids may cause hypernatremia, hypokalemia, fluid retention, and elevation in blood pressure. Large doses of any corticosteroid can demonstrate these effects, particularly if given for longer periods. Therapy with corticosteroids should be administered cautiously in patients with preexisting fluid retention, hypertension, congestive heart failure, and/or renal dysfunction. Dietary sodium restriction and potassium supplementation may be advisable.

References

  1. "Product Information. Hydeltrasol (prednisolone)." Merck & Co., Inc PROD (2001):
  2. "Product Information. Deltasone (prednisone)." Pharmacia and Upjohn PROD (2001):
  3. "Product Information. Decadron (dexamethasone)." Merck & Co., Inc PROD (2001):
  4. "Product Information. Hydrocortone (hydrocortisone)." Merck & Co., Inc PROD (2001):
  5. "Product Information. Medrol (methylprednisolone)." Pharmacia and Upjohn PROD (2001):
  6. "Product Information. Florinef Acetate (fludrocortisone)." Bristol-Myers Squibb PROD (2001):
  7. "Product Information. Cortone Acetate (cortisone)." Merck & Co., Inc PROD (2001):
  8. "Product Information. Kenalog (triamcinolone)." Bristol-Myers Squibb PROD (2001):
  9. "Product Information. Celestone (betamethasone)." Schering Corporation PROD (2001):
  10. "Product Information. Emflaza (deflazacort)." PTC Therapeutics, Inc. SUPPL-5 (2021):
  11. "Product Information. Agamree (vamorolone)." Santhera Pharmaceuticals (US) (2023):
View all 11 references
Moderate

High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)

Moderate Potential Hazard, Moderate plausibility

corticosteroids - hyperlipidemia

Corticosteroids may elevate serum triglyceride and LDL cholesterol levels if used for longer than brief periods. Patients with preexisting hyperlipidemia may require closer monitoring during prolonged corticosteroid therapy, and adjustments made accordingly in their lipid-lowering regimen.

References

  1. Seale JP, Compton MR "Side-effects of corticosteroid agents." Med J Aust 144 (1986): 139-42
  2. "Product Information. Hydeltrasol (prednisolone)." Merck & Co., Inc PROD (2001):
  3. "Product Information. Deltasone (prednisone)." Pharmacia and Upjohn PROD (2001):
  4. "Product Information. Decadron (dexamethasone)." Merck & Co., Inc PROD (2001):
  5. "Product Information. Hydrocortone (hydrocortisone)." Merck & Co., Inc PROD (2001):
  6. "Product Information. Medrol (methylprednisolone)." Pharmacia and Upjohn PROD (2001):
  7. "Product Information. Florinef Acetate (fludrocortisone)." Bristol-Myers Squibb PROD (2001):
  8. "Product Information. Cortone Acetate (cortisone)." Merck & Co., Inc PROD (2001):
  9. "Product Information. Kenalog (triamcinolone)." Bristol-Myers Squibb PROD (2001):
  10. "Product Information. Celestone (betamethasone)." Schering Corporation PROD (2001):
View all 10 references

Fludrocortisone drug interactions

There are 567 drug interactions with fludrocortisone.

Fludrocortisone disease interactions

There are 22 disease interactions with fludrocortisone which include:


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.