Xigduo XR (dapagliflozin / metformin) and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with Xigduo XR (dapagliflozin / metformin) which include:
Alcohol (Ethanol) ↔ dapagliflozin
Moderate Drug Interaction
Talk to your doctor before using ethanol together with dapagliflozin. Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. However, it may be best to limit alcohol intake to one drink daily for women and two drinks daily for men (1 drink = 5 oz wine, 12 oz beer, or 1.5 oz distilled spirits) in conjunction with your normal meal plan. Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Alcohol (Ethanol) ↔ metFORMIN
Moderate Drug Interaction
Ask your doctor before using ethanol together with metFORMIN. Taking this combination may cause a condition called lactic acidosis. Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain. Use alcohol cautiously. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safey take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, Moderate plausibility
SGLT-2 inhibitors - hyperlipidemia
There have been reports of dose-related increases in LDL cholesterol with the use of SGLT-2 inhibitors. Cholesterol levels should be monitored before and during treatment and appropriate therapy should be initiated if needed.
Xigduo XR (dapagliflozin / metformin) drug Interactions
There are 820 drug interactions with Xigduo XR (dapagliflozin / metformin)
Xigduo XR (dapagliflozin / metformin) disease Interactions
There are 8 disease interactions with Xigduo XR (dapagliflozin / metformin) which include:
- Bladder Cancer
- Lactic Acidosis
- Cardiovascular Risk
- Renal Dysfunction
- B12 Deficiency
Drug Interaction Classification
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.