Colchicine and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with colchicine.
Colchicine Food/Lifestyle
Major Food Interaction
Drinking large amounts of grapefruit juice can increase your blood levels of colchicine to dangerous levels. You should avoid the consumption of grapefruit or grapefruit juice during treatment with colchicine. Let your doctor know if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet, as these may be early symptoms of colchicine toxicity.
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Colchicine drug interactions
There are 312 drug interactions with colchicine.
Colchicine disease interactions
There are 7 disease interactions with colchicine which include:
- bone marrow suppression
- cardiac dysfunction
- DIC
- electrolyte disturbances
- liver disease
- renal dysfunction
- rhabdomyolysis
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
