Buprenorphine and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with buprenorphine.
buprenorphine Alcohol (Ethanol)
Major Drug Interaction
Using buprenorphine together with other medications that also cause central nervous system depression can lead to serious side effects such as respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Do not drink alcohol or self-medicate with these medications without your doctor's approval, and do not exceed the doses or frequency and duration of use prescribed by your doctor. Also, you should avoid driving or operating hazardous machinery until you know how these medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Buprenorphine drug interactions
There are 662 drug interactions with buprenorphine.
Buprenorphine disease interactions
There are 15 disease interactions with buprenorphine which include:
- impaired GI motility
- infectious diarrhea
- liver disease
- prematurity
- gastrointestinal obstruction
- acute MI
- drug dependence
- intracranial pressure
- respiratory depression
- adrenal insufficiency
- biliary spasm
- hypothyroidism
- renal dysfunction
- seizure disorders
- urinary retention
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- During pregnancy
- Support group
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
