Bendamustine and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with bendamustine.
Caffeine Bendamustine
Moderate Drug Interaction
MONITOR: Coadministration with inhibitors of CYP450 1A2 may increase the plasma concentrations of bendamustine, which has been shown in vitro to be metabolized by the isoenzyme.
MANAGEMENT: Caution is advised if bendamustine is used in combination with CYP450 1A2 inhibitors. Close monitoring for toxicity (e.g., neutropenia, thrombocytopenia, anemia, leukopenia, infections, bleeding complications) is recommended, and the bendamustine dosage adjusted as necessary.
References
- (2008) "Product Information. Treanda (bendamustine)." Cephalon Inc
Bendamustine drug interactions
There are 276 drug interactions with bendamustine.
Bendamustine disease interactions
There are 4 disease interactions with bendamustine which include:
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.