Topiramate Drug Interactions
Currently displaying a list of 291 drugs known to interact with topiramate.
- 108 major drug interactions
- 180 moderate drug interactions
- 3 minor drug interactions
Medications known to interact with topiramate
Note: Showing generic names only.
- acetazolamide
- acetylcarbromal
- acrivastine
- alfentanil
- allopurinol
- alprazolam
- amitriptyline
- amobarbital
- amoxapine
- anisindione
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- aripiprazole
- asenapine
- atropine
- azatadine
- baclofen
- belladonna
- bendroflumethiazide
- benzthiazide
- benztropine
- biperiden
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brinzolamide ophthalmic
- brivaracetam
- bromocriptine
- brompheniramine
- buprenorphine
- buspirone
- butabarbital
- butalbital
- butorphanol
- cannabidiol
- cannabis
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- cenobamate
- cetirizine
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorthalidone
- chlorzoxazone
- citalopram
- clemastine
- clidinium
- clobazam
- clomipramine
- clonidine
- clorazepate
- clozapine
- codeine
- cyclizine
- cyclobenzaprine
- cyproheptadine
- dantrolene
- daridorexant
- darifenacin
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- dichlorphenamide
- dicumarol
- dicyclomine
- difelikefalin
- digoxin
- dimenhydrinate
- diphenhydramine
- disopyramide
- divalproex sodium
- dorzolamide ophthalmic
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- droperidol
- drospirenone
- duloxetine
- entacapone
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- eszopiclone
- ethanol
- ethinyl estradiol
- ethotoin
- etonogestrel
- evening primrose
- ezogabine
- felbamate
- fenfluramine
- fentanyl
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosphenytoin
- gabapentin
- gabapentin enacarbil
- ganaxolone
- ginkgo
- glyburide
- glycerol phenylbutyrate
- glycopyrrolate
- glycopyrronium topical
- halazepam
- haloperidol
- heroin
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxychloroquine
- hydroxyzine
- hyoscyamine
- lasmiditan
- lemborexant
- levocetirizine
- levodopa
- levomethadyl acetate
- levomilnacipran
- levonorgestrel
- levorphanol
- lidocaine
- lithium
- lofexidine
- lorlatinib
- loxapine
- lumateperone
- lurasidone
- maprotiline
- meclizine
- medroxyprogesterone
- mefloquine
- melatonin
- mepenzolate
- meperidine
- mephenytoin
- meprobamate
- mesoridazine
- metaxalone
- metformin
- methadone
- methazolamide
- methdilazine
- methocarbamol
- methohexital
- methotrimeprazine
- methscopolamine
- methyclothiazide
- metoclopramide
- metolazone
- metyrosine
- midazolam
- milnacipran
- mitotane
- molindone
- morphine
- morphine liposomal
- olanzapine
- oliceridine
- olopatadine nasal
- opicapone
- opium
- orphenadrine
- oxazepam
- oxcarbazepine
- oxybutynin
- oxycodone
- oxymorphone
- paliperidone
- paraldehyde
- paroxetine
- pemoline
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- phenelzine
- phenindamine
- phenobarbital
- phentermine
- phenytoin
- pimozide
- pioglitazone
- polythiazide
- pramipexole
- pregabalin
- primidone
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propantheline
- propiomazine
- propoxyphene
- protriptyline
- pyrilamine
- safinamide
- scopolamine
- secobarbital
- selegiline
- sertraline
- sodium oxybate
- sodium phenylbutyrate
- sofpironium topical
- solifenacin
- stiripentol
- sufentanil
- suvorexant
- tapentadol
- tasimelteon
- temazepam
- tetrabenazine
- thalidomide
- thiethylperazine
- thioridazine
- thiothixene
- tizanidine
- tolterodine
- tramadol
- tranylcypromine
- trazodone
- triazolam
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- trospium
Topiramate alcohol/food interactions
There is 1 alcohol/food interaction with topiramate.
Topiramate disease interactions
There are 8 disease interactions with topiramate which include:
- oligohidrosis/hyperthermia
- suicidal tendency
- renal dysfunction
- metabolic acidosis
- angle closure glaucoma
- hemodialysis
- liver disease
- nephrolithiasis
Report options
More about topiramate
- topiramate consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (1,332)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: carbonic anhydrase inhibitor anticonvulsants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Aimovig
Learn about Aimovig (erenumab-aooe) a once-monthly, injectable medication that can be ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Qulipta
Qulipta is used to help prevent episodic or chronic migraine headaches in adults. Qulipta is an ...
Ubrelvy
Ubrelvy (ubrogepant) tablets are used for the acute treatment of migraine. Includes Ubrelvy side ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Vyepti
Vyepti (eptinezumab-jjmr) is used for the preventive treatment of migraine. Includes Vyepti ...
Celecoxib
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation ...
Pregabalin
Pregabalin may be used to treat certain types of pain and used in combination with other ...
Lorazepam
Lorazepam is in a group of drugs called benzodiazepines and is used to treat anxiety disorders ...
Propranolol
Propranolol is a beta-blocker that is used to treat tremors, chest pain, high blood pressure, heart ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
