Tolbutamide Drug Interactions
A total of 922 drugs (5946 brand and generic names) are known to interact with tolbutamide.
- 1 major drug interactions (3 brand and generic names)
- 830 moderate drug interactions (5414 brand and generic names)
- 91 minor drug interactions (529 brand and generic names)
Check for interactions with tolbutamide
Common medications checked in combination with tolbutamide
- Adrenalin (epinephrine)
- Aldactone (spironolactone)
- Ambien (zolpidem)
- Augmentin (amoxicillin / clavulanate)
- Colace (docusate)
- Cozaar (losartan)
- Easprin (aspirin)
- Ipratropium Inhalation Aerosol (ipratropium)
- Lantus (insulin glargine)
- Lasix (furosemide)
- Lipitor (atorvastatin)
- Nasonex (mometasone nasal)
- Norco (acetaminophen / hydrocodone)
- Norvasc (amlodipine)
- OxyContin (oxycodone)
- Paracetamol (acetaminophen)
- Plavix (clopidogrel)
- Singulair (montelukast)
- Spiriva (tiotropium)
- Zantac (ranitidine)
tolbutamide alcohol/food Interactions
There is 1 alcohol/food interaction with tolbutamide
tolbutamide disease Interactions
There are 6 disease interactions with tolbutamide which include:
- Cardiovascular Risk
- Dka
- Renal/Liver Disease
- Hypoglycemia
- Hemolytic Anemia/ G6Pd Deficiency
- Hyponatremia
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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