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Suphedrine (pseudoephedrine) Drug Interactions

A total of 290 drugs are known to interact with Suphedrine (pseudoephedrine).

  • 21 major drug interactions
  • 257 moderate drug interactions
  • 12 minor drug interactions

Show all medications in the database that may interact with Suphedrine (pseudoephedrine).

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Type in a drug name to check for interactions with Suphedrine (pseudoephedrine).

Most frequently checked interactions

View interaction reports for Suphedrine (pseudoephedrine) and the medicines listed below.

  • Allegra (fexofenadine)
  • alprazolam (Xanax, Xanax XR, Alprazolam Intensol, Niravam)
  • amoxicillin (Amoxil, Trimox, Apo-Amoxi, Amoxicot, Moxatag, DisperMox, Moxilin, Wymox, Biomox)
  • aspirin (Aspir 81, Ecotrin, Aspirin Low Strength, Acetylsalicylic Acid, Bayer Aspirin, Aspir-Low, Bufferin, Ascriptin, Arthritis Pain, Aspiritab, Aspergum, Fasprin, Halfprin, Easprin, Ecotrin Adult Low Strength, Empirin, Migralex, Aspi-Cor, St. Joseph 81 mg Chewable Aspirin, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Ecotrin Maximum Strength, Entercote, Bufferin Extra Strength, Ascriptin Enteric, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Bayer Aspirin Regimen, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspirtab, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Therapy Bayer, St. Joseph Aspirin, Stanback Analgesic, Norwich Aspirin, Acuprin 81, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Aspirin Lite Coat, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Benadryl (diphenhydramine)
  • cetirizine (Zyrtec, Equate Allergy Relief, Aller-Tec, All Day Allergy, All Day Allergy Children's, Aller-Tec Children's, PediaCare Children's 24-Hour Allergy, Children's Allergy Relief, Zyrtec Hives, Children's Zyrtec, Alleroff)
  • citalopram (Celexa)
  • Claritin (loratadine)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • guaifenesin (Mucinex, Robafen, Robitussin Chest Congestion, Tussin, Humibid, Guiatuss, Tussin Expectorant, Sorbutuss, Guaiatussin, Guaifenesin LA, Mucus Relief, Altarussin, Balminil Expectorant, Dristan Chesty Cough Guaiphenesin, Diabetic Tussin Mucus Relief, Mucinex Maximum Strength, Ganidin NR, Fenesin, Breonesin, Humavent LA, Lotussin, Diabetic Expectorant, Q-Tussin, Siltussin, Benylin E, Bidex-400, Humibid E, Buckley's Chest Congestion, Refenesen Chest Congestion Relief, Benadryl Chesty Forte, G Bid, Touro EX, Pneumomist, Iofen-NF, Humibid Pediatric, Organ-1 NR, Iodrol NR, Mucinex Children's Chest Congestion, Guaibid-LA, Aquamist, Q-Bid LA, Amibid LA, Mucobid-LA, Guaifenex LA, Fenex-LA, Muco-Fen LA, Liquibid, Muco-Fen 800, Scot-Tussin Expectorant, Guiacough, GG 200 NR, Glytuss, Anti-Tuss, Allfen Jr, Genatuss, Halotussin, Mastussin, Mytussin, Ri-Tussin, Robichem, Siltuss DAS, T-Tussin, Tusscidin, Gua-SR, Humigen LA, Sinumist, Altorant, Duratuss G, Robitussin Mucus + Chest Congestion, Diabetic Tuss, Naldecon-EX Senior, Phanasin, Guaifenex G, Iophen NR, GG-Cen, Muco-Fen 1200, Liquidbid LA, Liquidbid 1200, Calmylin Expectorant, Guiadrine G-1200, Siltussin DAS-NA, Iofen, Muco-Fen, Drituss G, Beechams Veno's for Kids Chesty Cough, Junior Meltus Colour and Sugar Free Expectorant, Help I Have Chest Congestion, Tixylix Chesty Cough, Xpect, Fenesin IR, Hill's Balsam Chesty Cough, Jackson's Extra Strength All Fours, Junior Meltus Chesty Coughs with Catarrh, Liqufruta Garlic Cough Medicine, Family Meltus Chesty Coughs, Jackson's The Original All Fours, Beechams Veno's Expectorant, Lemsip Cough Chesty, Respa-GF, Nirolex Chesty Cough, Dristan Chesty Cough, Nyal Chesty Cough, Strepsils Chesty Cough, Kenkay Chesty Cough Eexpectorant, Pharmacist Expectorant, Mucinex for Kids, Guaifen NR, Liquituss GG, Lloydspharmacy Expectorant Adult Cough, Lloydspharmacy Expectorant Junior Cough, TabTussin 400, Siltussin DAS, Bronchoril, Hytuss, Organidin NR, Actifed CC Chesty Cough, Mucaplex, Tussin Mucus + Chest Congestion, Air Power)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Euthyrox, Unithroid, Levothyrox, Eutroxsig, Levo-T, Oroxine, L Thyroxine Roche, Levotabs, Novothyrox, Tirosint-Sol, Levotec, Evotrox)
  • loratadine (Claritin, Alavert, Claritin 24 Hour Allergy, Loratadine Reditab, Allergy Relief Tablets, Allergy Relief 24 Hour, Claritin Reditabs, Wal-itin, Children's Allergy Relief 24 Hour, Vicks QlearQuil All Day & All Night 24 Hour Allergy Relief, Help I Have Allergies, ohm Allergy Relief, Clear-Atadine, Claritin Hives Relief, Dimetapp Children's ND Non-Drowsy Allergy, Clear-Atadine Children's, Bactimicina Allergy, Tavist ND, Children's Claritin Allergy)
  • montelukast (Singulair)
  • Mucinex (guaifenesin)
  • multivitamin (Daflon, Metanx, Neurobion, Vitamins, Theragran, Vitamin B Complex 100, Cerefolin NAC, Cerefolin, Rena-Vite, Folbic, Foltx, Estroven, Nephro-Vite, Lipoflavonoid, Folbee, Foltanx, Thera, Super B Complex, MVI Adult, Nephrocaps, PoDiaPN, Folic Acid XTRA, Tab-A-Vite, Cod Liver Oil Mint, B Complex 100, Triphrocaps, FaBB, Nufola, Nephro-Vite Rx, Cod Liver Oil, Multi Vitamin+, Rheumate, Renal Caps, Essentiale, Berocca, Daily Vite, Rena-Vite Rx, Xyzbac, Lysiplex, Flintstones Multivitamins, Surbex, Super B-50, Fletanol, Infuvite, Infuvite Pediatric, Folcaps, Folinic-Plus, StressTabs, Reno Caps, Surbex with C, Folika-T, Apetigen, Stress Formula, B Complex 50, Cernevit, Vitamin Daily Liquid, Topfit Vitamin B Complex, Vitamin B Compound Strong, Nephronex, Folgard RX, One-A-Day Men's Health Formula, Folplex, Nephplex Rx, Metafolbic Plus, Virt-Caps, Therems, Daily Multiple Vitamins, Childrens Chewable Multivitamins, Vitacirc-B, One-A-Day Essentials, Essential Balance, Flintstones with C Multivitamins, Stress B with C, Theravite, Thera-Plus, High Potency B Complex with B12 and C, Super B-100 TD, L-methylfolate Ca, Me-Cbl NAC, Theragenerix, Apetex, Folastin, Topfit Vitamin B Complex Forte, L-Methyl-B6-B12, Jetepar, Vitamin A and D Concentrate, Centrum 8400, Foltabs 800, Menopause Relief with Lifenol, Daily-Vite Men's Formula, Biotin Forte, Vimar, B 100 Complex, Vol-Care Rx, Folbic RF, Foltanx RF, Mebolex, Mebolic, B-Plex, Vitaplex, Metafolbic, Stress-600, Thera-Tabs, Vi-Daylin, Poly-Vi-Sol, Watkins Harvest, Balanced B-100, B-Stress, B-Scorbic, Bee with C, Balanced B-50, Nat-Rul B-125, Balanced B-150, Unicap Capsule, Unicap Jr, Unicap, Optilets-500, Super Plenamins, Vitamins for Hair, Vi-Daylin Chewable, Folast, Enfolast, Sunkist Child Chewable with C, Enfolast-N, Sunkist Child Chewable, Poly-Vi-Sol Chewable, Neurpath-B, Fruity Chew, Triphro, Poly-Vit Chew, Vita-Respa, Chewable-Vite, Bugs Bunny with Extra C, Geravine, Bounty Bear Vitamins, Garfield Vitamins, Vi-Daylin Drops, Poly-Vi-Sol Drops, Baby Vitamin Drop, Vita Drop, Poly Vit Drops, MVC SDV, Glutofac, Allbee-C, Vitabee with C, High Potency B+C, Av-VITE FB, Farbee with C, Mynephron, Renatabs, Tri-Vitamin, DEKAs Essential, Vitamin B-50, Vitamin B-100, D-400 international units, Vitamin B-100 T/R, Hexavitamin, Celebrate B-12, Kenwood Therapeutic, Oncovite, Glycogenics, Beminal-500, Tri-Vit Drops, Flintstones Toddler, One Tab Daily, Vitamin C, E, and Rose Hips, Scotts Emulsion, Stress Formula 600, Tri-Vit, Mega B, Apatate, T-Vites, Hylavite, High B Complex, L-methylfolate Ca, P-5-P, Me-Cbl, Prostate 2.4, MTX Support, Cardiotek, Beminal, Beminal with C Fortis, Full Spectrum B with C, Bugs Bunny Multiple Vitamins, Allbee with C, Prevital, Surbex Filmtab, Tender Age Vitamin ADC, Folgard Rx 2.2, Cernevit-12, SeroSyn, Diatx, Vitamin A, D, One-A-Day 50+, Thex Forte, Metafolbic Plus RF, Dosoquin, Protegra Cardio, Virt-Vite Plus, K2 Plus D3, Renaphro, Virt-Gard, Dialyvite Rx, L-Methyl-MC, Levomefolate Calcium-Algal Powder, VP-Vite Rx, Vesselvite, Folbee Plus, Combgen, Abidec, Unichem Multivitamin, Health Aid Multivitamin, AllanTex, One Daily Multi-Essential, Larobec, Foltrate, Cardiotek Rx, Folbalin Plus, Dialyvite 800, Folbalin, Multi-Delyn, Multi Vits with Beta Carotene, Foleve Plus, Folnate, Folnate Plus, B-Complex with B-12, Foleve, Hair, Skin, & Nails Gummies, Folamin, DexFol, Equaline One Daily Essential, Av-VITE FB Forte, Folmor, Zycose, Vigomar Forte, Allbee Plus, Triveen-CF, Nature's Bounty Hair Skin & Nails, Total B with C, Methaver, GNC Women's Hair, Skin & Nails Formula, Folbee AR, NuFol, Co-Veratrol, Methazel, Dyzbac, Mynephrocaps, Omega Q Plus, Acnepril, Super Theravite-M, Primaplex, Becomject-100, Poly-Vita Drops, MVI-12, B-Ject 100, L-Methyl-MC NAC, Therobec, Formula B, Tri-Vi-Sol, TL Gard, Vi-Daylin ADC, Lipogen, Nephrocaps QT, Virt-Vite, Lipotriad, Virt-Vite Forte, Folplex 2.2, Cholinoid, Tri-Vita Drops, Liponol, Bee-Comp with C, Cholidase, Vita-Plus G, Rovin-CF, Cota-B-Plex, 1000 BC, Neurodep, Neuroforte-Six, MVI Pediatric, B-Plex Plus, Nephrolan Rx, Ivites Rx, Zymacap, Dayalets, Sigtab, Allbee-C 800, Cefol, B-Complex SR, Protegra, Wellesse Sugar Free Childrens Multivitamin Gummies, Alz-Nac, Sesame St Vitamins with Extra C, Surbex-T, Male Formula, Superplex-T, Vi-Stress, T-BMP, Animal Shape Vitamins, B-50 Complex, Niva-Fol)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Paracetamol (acetaminophen)
  • simvastatin (Zocor, FloLipid)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Tylenol (acetaminophen)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)
  • zolpidem (Ambien, Ambien CR, Zolpimist, Intermezzo, Edluar)
  • Zyrtec (cetirizine)

Suphedrine (pseudoephedrine) disease interactions

There are 6 disease interactions with Suphedrine (pseudoephedrine) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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