Lyrica Drug Interactions
Currently displaying a list of 286 drugs known to interact with Lyrica (pregabalin).
- 28 major drug interactions
- 257 moderate drug interactions
- 1 minor drug interaction
Medications known to interact with Lyrica
Note: Showing generic names only.
- acetylcarbromal
- acrivastine
- alfentanil
- aliskiren
- allopurinol
- alprazolam
- amitriptyline
- amobarbital
- amoxapine
- apomorphine
- apraclonidine ophthalmic
- aripiprazole
- asenapine
- azatadine
- azelastine nasal
- azilsartan medoxomil
- baclofen
- benazepril
- benztropine
- biperiden
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- buprenorphine
- buspirone
- butabarbital
- butalbital
- butorphanol
- candesartan
- cannabidiol
- cannabis
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- cenobamate
- cetirizine
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorzoxazone
- citalopram
- clemastine
- clobazam
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- codeine
- cyclizine
- cyclobenzaprine
- cyproheptadine
- dantrolene
- daridorexant
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- difelikefalin
- dimenhydrinate
- diphenhydramine
- divalproex sodium
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- droperidol
- duloxetine
- enalapril
- enalaprilat
- entacapone
- eprosartan
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- eszopiclone
- ethanol
- ethchlorvynol
- ethosuximide
- ethotoin
- evening primrose
- ezogabine
- felbamate
- fenfluramine
- fentanyl
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosinopril
- fosphenytoin
- lamotrigine
- lasmiditan
- lemborexant
- levetiracetam
- levocetirizine
- levodopa
- levomethadyl acetate
- levomilnacipran
- levorphanol
- lidocaine
- lisinopril
- lithium
- lofexidine
- lorazepam
- losartan
- loxapine
- lumateperone
- lurasidone
- maprotiline
- meclizine
- mefloquine
- melatonin
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methdilazine
- methocarbamol
- methohexital
- methotrimeprazine
- methsuximide
- metoclopramide
- metyrosine
- midazolam
- milnacipran
- mirabegron
- mirtazapine
- mitotane
- moexipril
- molindone
- morphine
- morphine liposomal
- olanzapine
- oliceridine
- olmesartan
- olopatadine nasal
- opicapone
- opium
- orphenadrine
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- paliperidone
- paraldehyde
- paramethadione
- paroxetine
- pemoline
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perindopril
- perphenazine
- phenacemide
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phenytoin
- pimozide
- pioglitazone
- pramipexole
- primidone
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propiomazine
- propoxyphene
- protriptyline
- pyrilamine
- ramelteon
- ramipril
- rasagiline
- remifentanil
- remimazolam
- risperidone
- ropinirole
- rosiglitazone
- rotigotine
- rufinamide
- safinamide
- scopolamine
- secobarbital
- selegiline
- sertraline
- sibutramine
- sodium oxybate
- st. john's wort
- stiripentol
- sufentanil
- suvorexant
- tapentadol
- tasimelteon
- telmisartan
- temazepam
- tetrabenazine
- thalidomide
- thiethylperazine
- thiopental
- thioridazine
- thiothixene
- tiagabine
- tizanidine
- tolcapone
- topiramate
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- triazolam
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- troglitazone
- valbenazine
- valerian
- valproic acid
- valsartan
- venlafaxine
- vibegron
- vigabatrin
- vilazodone
- vortioxetine
Lyrica alcohol/food interactions
There is 1 alcohol/food interaction with Lyrica (pregabalin).
Lyrica disease interactions
There are 6 disease interactions with Lyrica (pregabalin) which include:
- drug dependence
- suicidal tendency
- angioedema
- creatine kinase elevations
- peripheral edema
- PR interval prolongation
Report options
More about Lyrica (pregabalin)
- Lyrica consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (928)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- FDA approval history
- Drug class: gamma-aminobutyric acid analogs
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Carbamazepine
Carbamazepine is used to treat epileptic seizures and nerve pain such as trigeminal neuralgia ...
Lidocaine topical
Lidocaine topical is used for anal itching, anesthesia, burns, external, gastrointestinal surgery ...
Mounjaro
Mounjaro is used for type 2 diabetes to help lower blood sugar levels. Mounjaro has also been shown ...
Lamictal
Lamictal is an anti-epileptic medication used treat seizures in adults and children over 2 years ...
Levetiracetam
Levetiracetam is used for bipolar disorder, epilepsy, hyperekplexia, neuralgia, new daily ...
Cymbalta
Cymbalta (duloxetine) is used to treat major depressive disorder, general anxiety disorder and ...
Topiramate
Topiramate is used for bipolar disorder, borderline personality disorder, bulimia, diabetic ...
Medrol
Medrol is used for allergic rhinitis, asthma, asthma, acute, asthma, maintenance, congenital ...
Lorazepam
Lorazepam is in a group of drugs called benzodiazepines and is used to treat anxiety disorders ...
Methylprednisolone
Methylprednisolone is used to treat conditions such as allergies, arthritis, lupus and ulcerative ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
