Phenylephrine/promethazine Interactions
There are 735 drugs known to interact with phenylephrine/promethazine, along with 17 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 122 are major, 598 are moderate, and 15 are minor.
- View all 735 medications that may interact with phenylephrine/promethazine
- View phenylephrine/promethazine alcohol/food interactions (3)
- View phenylephrine/promethazine disease interactions (17)
Most frequently checked interactions
View interaction reports for phenylephrine / promethazine and the medicines listed below.
- Ambien (zolpidem)
- Aspirin Low Strength (aspirin)
- Ativan (lorazepam)
- BuSpar (buspirone)
- Crestor (rosuvastatin)
- Keppra (levetiracetam)
- Klonopin (clonazepam)
- Lasix (furosemide)
- Levothroid (levothyroxine)
- Metoprolol Succinate ER (metoprolol)
- Morphine Sulfate ER (morphine)
- Norco (acetaminophen / hydrocodone)
- Premarin (conjugated estrogens)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Voltaren (diclofenac)
- Xanax (alprazolam)
Phenylephrine/promethazine alcohol/food interactions
There are 3 alcohol/food interactions with phenylephrine / promethazine.
Phenylephrine/promethazine disease interactions
There are 17 disease interactions with phenylephrine / promethazine which include:
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
- BPH
- diabetes
- glaucoma
Report options
More about phenylephrine / promethazine
- phenylephrine/promethazine consumer information
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- Pricing & coupons
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.