Promethazine VC Plain Interactions
There are 734 drugs known to interact with Promethazine VC Plain (phenylephrine/promethazine), along with 17 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 121 are major, 598 are moderate, and 15 are minor.
- View all 734 medications that may interact with Promethazine VC Plain
- View Promethazine VC Plain alcohol/food interactions (3)
- View Promethazine VC Plain disease interactions (17)
Most frequently checked interactions
View interaction reports for Promethazine VC Plain (phenylephrine / promethazine) and the medicines listed below.
- albuterol
- alprazolam
- Ambien (zolpidem)
- amlodipine
- bupropion
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- fluconazole
- furosemide
- gabapentin
- hydrochlorothiazide
- hydroxyzine
- ibuprofen
- levothyroxine
- lisinopril
- meloxicam
- metformin
- Norvasc (amlodipine)
- omeprazole
- oxycodone
- pantoprazole
- prednisone
- promethazine
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
Promethazine VC Plain alcohol/food interactions
There are 3 alcohol/food interactions with Promethazine VC Plain (phenylephrine / promethazine).
Promethazine VC Plain disease interactions
There are 17 disease interactions with Promethazine VC Plain (phenylephrine / promethazine) which include:
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
- BPH
- diabetes
- glaucoma
Report options
More about Promethazine VC Plain (phenylephrine / promethazine)
- Promethazine VC Plain consumer information
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.