Extendryl PEM Interactions
There are 351 drugs known to interact with Extendryl PEM (methscopolamine / phenylephrine), along with 21 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 32 are major, 300 are moderate, and 19 are minor.
- View Extendryl PEM alcohol/food interactions (3)
- View Extendryl PEM disease interactions (21)
Medications known to interact with Extendryl PEM
Note: Showing generic names only.
- abobotulinumtoxinA
- acarbose
- acebutolol
- acetaminophen
- acetohexamide
- acetylcholine ophthalmic
- aclidinium
- acrivastine
- albiglutide
- albuterol
- alfentanil
- alogliptin
- amantadine
- ambenonium
- aminophylline
- amitriptyline
- amoxapine
- amphetamine
- apraclonidine ophthalmic
- arbutamine
- arformoterol
- aripiprazole
- armodafinil
- asenapine
- atenolol
- atomoxetine
- atropine
- atropine ophthalmic
- azatadine
- belladonna
- bendroflumethiazide
- benzgalantamine
- benzphetamine
- benzthiazide
- benztropine
- betaxolol
- betaxolol ophthalmic
- bethanechol
- bexagliflozin
- biperiden
- bisoprolol
- bitolterol
- brexpiprazole
- brompheniramine
- buprenorphine
- bupropion
- butorphanol
- caffeine
- canagliflozin
- carbachol ophthalmic
- carbinoxamine
- cariprazine
- carteolol
- carteolol ophthalmic
- carvedilol
- cevimeline
- chlorcyclizine
- chlorothiazide
- chlorpheniramine
- chlorpromazine
- chlorpropamide
- chlorthalidone
- cisapride
- clemastine
- clidinium
- clomipramine
- clozapine
- cocaine nasal
- cocaine topical
- codeine
- colchicine
- cyclizine
- cyclobenzaprine
- cyclopentolate ophthalmic
- cyproheptadine
- dapagliflozin
- darifenacin
- daxibotulinumtoxinA
- demecarium bromide ophthalmic
- deserpidine
- desipramine
- desvenlafaxine
- dexbrompheniramine
- dexchlorpheniramine
- dexmethylphenidate
- dextroamphetamine
- dezocine
- dicyclomine
- diethylpropion
- digitoxin
- digoxin
- dihydroergotamine
- dimenhydrinate
- diphenhydramine
- disopyramide
- dobutamine
- donepezil
- dopamine
- doxapram
- doxepin
- doxepin topical
- doxylamine
- droxidopa
- dulaglutide
- duloxetine
- echothiophate iodide ophthalmic
- edrophonium
- eluxadoline
- empagliflozin
- ephedrine
- epinephrine
- epoprostenol
- ergonovine
- ergotamine
- ertugliflozin
- esmolol
- ethanol
- exenatide
- galantamine
- glimepiride
- glipizide
- glyburide
- glycopyrrolate
- glycopyrronium topical
- guanadrel
- guanethidine
- guanidine
- haloperidol
- halothane
- homatropine ophthalmic
- hyaluronidase
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxyzine
- hyoscyamine
- iloperidone
- iloprost
- imipramine
- incobotulinumtoxinA
- indacaterol
- indapamide
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iobenguane I 123
- iobenguane I 131
- ipratropium
- ipratropium nasal
- isocarboxazid
- isoetharine
- isoflurophate ophthalmic
- isoproterenol
- labetalol
- landiolol
- letibotulinumtoxinA
- levalbuterol
- levobetaxolol ophthalmic
- levobunolol ophthalmic
- levodopa
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levorphanol
- levothyroxine
- linagliptin
- linezolid
- liothyronine
- liraglutide
- lisdexamfetamine
- lithium
- lixisenatide
- loperamide
- loxapine
- lumateperone
- lurasidone
- ma huang
- maprotiline
- mazindol
- mecamylamine
- meclizine
- mepenzolate
- meperidine
- mephentermine
- mesoridazine
- metaproterenol
- metaraminol
- metformin
- methadone
- methamphetamine
- methdilazine
- methotrimeprazine
- methoxamine
- methyclothiazide
- methyldopa
- methylene blue
- methylergonovine
- methylphenidate
- methysergide maleate
- metipranolol ophthalmic
- metoclopramide
- metolazone
- metoprolol
- midodrine
- miglitol
- milnacipran
- modafinil
- molindone
- morphine
- morphine liposomal
- nadolol
- nalbuphine
- nateglinide
- nebivolol
- neostigmine
- nitrofurantoin
- nitroglycerin
- norepinephrine
- nortriptyline
- olanzapine
- oliceridine
- olodaterol
- onabotulinumtoxinA
- opium
- orphenadrine
- oxybutynin
- oxycodone
- oxymorphone
- oxytocin
- ozanimod
- paliperidone
- penbutolol
- pentazocine
- perphenazine
- phendimetrazine
- phenelzine
- phenindamine
- phentermine
- phenylephrine ophthalmic
- phenylpropanolamine
- physostigmine
- physostigmine ophthalmic
- pilocarpine
- pilocarpine ophthalmic
- pimozide
- pindolol
- pioglitazone
- pirbuterol
- polythiazide
- potassium chloride
- potassium citrate
- prabotulinumtoxinA
- pramlintide
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propantheline
- propiomazine
- propoxyphene
- propranolol
- protriptyline
- prucalopride
- pseudoephedrine
- pyridostigmine
- pyrilamine
- racepinephrine
- rasagiline
- rauwolfia serpentina
- remifentanil
- repaglinide
- reserpine
- revefenacin
- rimabotulinumtoxinB
- risperidone
- ritodrine
- rivastigmine
- rosiglitazone
- safinamide
- salmeterol
- saxagliptin
- scopolamine
- scopolamine ophthalmic
- secretin
- selegiline
- selexipag
- semaglutide
- sibutramine
- sitagliptin
- solifenacin
- solriamfetol
- sotagliflozin
- sotalol
- sufentanil
- tacrine
- tapentadol
- terbutaline
- theophylline
- thiethylperazine
- thioridazine
- thiothixene
- thyroid desiccated
- timolol
- timolol ophthalmic
- tiotropium
- tirzepatide
- tolazamide
- tolbutamide
- tolterodine
- topiramate
- tramadol
- tranylcypromine
- treprostinil
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimipramine
- tripelennamine
- triprolidine
- troglitazone
- tropicamide ophthalmic
- trospium
Extendryl PEM alcohol/food interactions
There are 3 alcohol/food interactions with Extendryl PEM (methscopolamine / phenylephrine).
Extendryl PEM disease interactions
There are 21 disease interactions with Extendryl PEM (methscopolamine / phenylephrine) which include:
- autonomic neuropathy
- GI obstruction
- glaucoma
- obstructive uropathy
- reactive airway diseases
- myasthenia gravis
- infectious diarrhea
- cardiovascular disease
- cardiac disease
- tachycardia
- coronary artery disease
- gastric ulcer
- gastroesophageal reflux
- ulcerative colitis
- BPH
- diabetes
- glaucoma
- hypertension
- hyperthyroidism
- diarrhea
- fever
Report options
More about Extendryl PEM (methscopolamine / phenylephrine)
- Compare alternatives
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.