Opsumit Drug Interactions
Currently displaying a list of 210 drugs known to interact with Opsumit (macitentan).
- 49 major drug interactions
- 158 moderate drug interactions
- 3 minor drug interactions
Medications known to interact with Opsumit
Note: Showing generic names only.
- abametapir topical
- adagrasib
- aminoglutethimide
- amiodarone
- amobarbital
- amprenavir
- apalutamide
- apomorphine
- aprepitant
- arginine
- armodafinil
- asciminib
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- atazanavir
- avacopan
- bedaquiline
- belzutifan
- berotralstat
- bexarotene
- black cohosh
- boceprevir
- bosentan
- brentuximab
- brigatinib
- butabarbital
- butalbital
- calaspargase pegol
- cannabidiol
- capivasertib
- carbamazepine
- cenobamate
- ceritinib
- chloramphenicol
- cimetidine
- ciprofloxacin
- citrulline
- clarithromycin
- clofarabine
- clofazimine
- clotrimazole
- cobicistat
- conivaptan
- crizotinib
- cyclosporine
- dabrafenib
- daclizumab
- danazol
- daridorexant
- darunavir
- dasatinib
- deferasirox
- delavirdine
- dexamethasone
- diltiazem
- dronedarone
- duvelisib
- echinacea
- efavirenz
- elafibranor
- elagolix
- encorafenib
- entrectinib
- enzalutamide
- epirubicin
- erythromycin
- eslicarbazepine
- etranacogene dezaparvovec
- etravirine
- fedratinib
- felbamate
- fenfluramine
- fenofibrate
- fenofibric acid
- fexinidazole
- fidanacogene elaparvovec
- finerenone
- fluconazole
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- idelalisib
- imatinib
- indinavir
- interferon beta-1a
- interferon beta-1b
- iptacopan
- isavuconazonium
- isoniazid
- itraconazole
- ivacaftor
- ivosidenib
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lenacapavir
- lesinurad
- letermovir
- levodopa
- levoketoconazole
- lofexidine
- lomitapide
- lonafarnib
- lonapegsomatropin
- lorlatinib
- mavacamten
- mavorixafor
- mephobarbital
- methotrexate
- metreleptin
- mibefradil
- miconazole
- mifepristone
- mipomersen
- mitapivat
- mitotane
- mobocertinib
- modafinil
- pacritinib
- palbociclib
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pentobarbital
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pirtobrutinib
- pitolisant
- posaconazole
- pralsetinib
- primidone
- ranolazine
- remdesivir
- repotrectinib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- ritlecitinib
- ritonavir
- rucaparib
- rufinamide
- saquinavir
- secobarbital
- selpercatinib
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotorasib
- sparsentan
- st. john's wort
- stiripentol
- sulfinpyrazone
- suvorexant
- suzetrigine
- tazemetostat
- tecovirimat
- telaprevir
- telithromycin
- telotristat
- teriflunomide
- thioguanine
- ticagrelor
- tovorafenib
- trabectedin
- treosulfan
- trofinetide
- troglitazone
- troleandomycin
- tucatinib
- vadadustat
- valoctocogene roxaparvovec
- vemurafenib
- verapamil
- viloxazine
- vorasidenib
- voriconazole
- voxelotor
Opsumit disease interactions
There are 3 disease interactions with Opsumit (macitentan) which include:
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- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: agents for pulmonary hypertension
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
