Larotrectinib Interactions
There are 511 drugs known to interact with larotrectinib, along with 1 disease interaction, and 1 alcohol/food interaction. Of the total drug interactions, 67 are major, 424 are moderate, and 20 are minor.
- View larotrectinib alcohol/food interactions (1)
- View larotrectinib disease interactions (1)
Medications known to interact with larotrectinib
Note: Showing generic names only.
A
- abemaciclib
- abrocitinib
- acalabrutinib
- adagrasib
- ado-trastuzumab emtansine
- albendazole
- alfentanil
- alfuzosin
- aliskiren
- alpelisib
- alprazolam
- aminoglutethimide
- amiodarone
- amlodipine
- amobarbital
- amprenavir
- apalutamide
- apixaban
- aprepitant
- aripiprazole
- armodafinil
- asciminib
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atazanavir
- atezolizumab
- atogepant
- atorvastatin
- avacopan
- avanafil
- avapritinib
- avelumab
- axitinib
B
- bedaquiline
- belzutifan
- bepridil
- berotralstat
- betamethasone
- bexarotene
- bicalutamide
- black cohosh
- boceprevir
- bosentan
- bosutinib
- brentuximab
- brexpiprazole
- brigatinib
- bromocriptine
- budesonide
- budesonide nasal
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
C
- cabazitaxel
- cabozantinib
- calaspargase pegol
- cannabidiol
- capivasertib
- capmatinib
- carbamazepine
- cariprazine
- carvedilol
- cemiplimab
- cenobamate
- ceritinib
- cerivastatin
- cevimeline
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- chlorotrianisene
- cilostazol
- cimetidine
- ciprofloxacin
- cisapride
- citalopram
- clarithromycin
- clofarabine
- clonazepam
- clotrimazole
- cobicistat
- cobimetinib
- colchicine
- conivaptan
- conjugated estrogens
- copanlisib
- cortisone
- cosibelimab
- crizotinib
- cyclosporine
D
- dabrafenib
- daclatasvir
- daclizumab
- danazol
- danicopan
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- deferasirox
- deflazacort
- dehydroepiandrosterone
- delavirdine
- deucravacitinib
- dexamethasone
- dihydroergotamine
- diltiazem
- disopyramide
- docetaxel
- dofetilide
- dolasetron
- donepezil
- doravirine
- dostarlimab
- doxazosin
- doxorubicin
- doxorubicin liposomal
- dronabinol
- dronedarone
- droperidol
- drospirenone
- durvalumab
- dutasteride
- duvelisib
E
- efavirenz
- elacestrant
- elafibranor
- elagolix
- eletriptan
- eliglustat
- eltrombopag
- encorafenib
- enfortumab vedotin
- entrectinib
- enzalutamide
- epirubicin
- eplerenone
- ergonovine
- ergotamine
- erlotinib
- erythromycin
- escitalopram
- eslicarbazepine
- esomeprazole
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethinyl estradiol
- ethosuximide
- etonogestrel
- etoposide
- etranacogene dezaparvovec
- etrasimod
- etravirine
- everolimus
F
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fentanyl
- fesoterodine
- fexinidazole
- fidanacogene elaparvovec
- fidaxomicin
- finasteride
- finerenone
- flibanserin
- fluconazole
- fludrocortisone
- flurazepam
- fluticasone
- fluvastatin
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- futibatinib
G
- ganaxolone
- gefitinib
- gepirone
- gilteritinib
- givinostat
- glasdegib
- glyburide
- glycerol phenylbutyrate
- goldenseal
- granisetron
- grepafloxacin
- griseofulvin
- guanfacine
H
- halofantrine
- haloperidol
- halothane
- hydrocodone
- hydrocortisone
- hydroxychloroquine
- hydroxyprogesterone
I
- ibrutinib
- idelalisib
- iloperidone
- imatinib
- imipramine
- indacaterol
- indinavir
- infigratinib
- interferon beta-1a
- interferon beta-1b
- ipilimumab
- iptacopan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isoniazid
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivermectin
- ivosidenib
- ixabepilone
K
L
- lanreotide
- lapatinib
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- leniolisib
- lesinurad
- letermovir
- letrozole
- levacetylleucine
- levamlodipine
- levobupivacaine
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- lidocaine
- lomitapide
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- loratadine
- lorlatinib
- losartan
- lovastatin
- lumateperone
- lurasidone
- lurbinectedin
M
- macitentan
- maraviroc
- mavacamten
- mavorixafor
- medroxyprogesterone
- mefloquine
- megestrol
- meperidine
- mephobarbital
- methadone
- methotrexate
- methylergonovine
- methylprednisolone
- methysergide maleate
- metreleptin
- mibefradil
- miconazole
- midazolam
- midostaurin
- mifepristone
- mipomersen
- mirabegron
- mirtazapine
- mitapivat
- mitotane
- mobocertinib
- modafinil
- momelotinib
- montelukast
N
- nafcillin
- naldemedine
- naloxegol
- naltrexone
- nateglinide
- nefazodone
- nelfinavir
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nimodipine
- nintedanib
- niraparib
- nirogacestat
- nisoldipine
- nitisinone
- nivolumab
- norethindrone
- norgestrel
O
- octreotide
- olaparib
- oliceridine
- olutasidenib
- omeprazole
- ondansetron
- oritavancin
- osilodrostat
- osimertinib
- oteseconazole
- oxcarbazepine
- oxybutynin
- oxycodone
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- palovarotene
- panobinostat
- pantoprazole
- paricalcitol
- pasireotide
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pembrolizumab
- pemigatinib
- pentobarbital
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pimavanserin
- pimecrolimus topical
- pimozide
- pioglitazone
- pirtobrutinib
- pitolisant
- polatuzumab vedotin
- pomalidomide
- ponatinib
- posaconazole
- pralsetinib
- praziquantel
- prednisolone
- prednisone
- pretomanid
- primidone
- progesterone
- progesterone topical
- propafenone
Q
R
- ramelteon
- ranolazine
- red yeast rice
- regorafenib
- remdesivir
- repaglinide
- repotrectinib
- resmetirom
- retapamulin topical
- retifanlimab
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilpivirine
- rimegepant
- ripretinib
- risperidone
- ritlecitinib
- ritonavir
- rivaroxaban
- roflumilast topical
- rolapitant
- romidepsin
- ropivacaine
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- safinamide
- salmeterol
- saquinavir
- sarecycline
- saxagliptin
- secobarbital
- selexipag
- selpercatinib
- selumetinib
- sertraline
- sibutramine
- sildenafil
- silodosin
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sonidegib
- sorafenib
- sotorasib
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- sufentanil
- sulfinpyrazone
- sunitinib
- suvorexant
- suzetrigine
T
- tacrolimus
- tadalafil
- tamoxifen
- tamsulosin
- tasimelteon
- tazemetostat
- tecovirimat
- telaprevir
- telithromycin
- telotristat
- temsirolimus
- teniposide
- tepotinib
- terbinafine
- terfenadine
- teriflunomide
- testosterone
- testosterone topical
- theophylline
- thioguanine
- thiotepa
- tiagabine
- ticagrelor
- tinidazole
- tislelizumab
- tivozanib
- tofacitinib
- tolterodine
- tolvaptan
- toremifene
- toripalimab
- tovorafenib
- trabectedin
- tramadol
- trazodone
- tremelimumab
- treosulfan
- tretinoin
- triamcinolone
- triazolam
- trofinetide
- troglitazone
- troleandomycin
- tucatinib
U
V
- vadadustat
- valbenazine
- valdecoxib
- valoctocogene roxaparvovec
- vandetanib
- vardenafil
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vilazodone
- viloxazine
- vimseltinib
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vonoprazan
- vorapaxar
- vorasidenib
- voriconazole
- voxelotor
W
Z
Larotrectinib alcohol/food interactions
There is 1 alcohol/food interaction with larotrectinib.
Larotrectinib disease interactions
There is 1 disease interaction with larotrectinib which include:
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More about larotrectinib
- larotrectinib consumer information
- Compare alternatives
- Reviews (1)
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: multikinase inhibitors
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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