Larotrectinib and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with larotrectinib.
Larotrectinib Food
Moderate Food Interaction
Grapefruit juice can increase the blood levels of larotrectinib. This may increase the risk and/or severity of side effects such as dizziness, confusion, coordination problems, memory problems, liver problems, and tingling, numbness or burning in the hands and feet. You should avoid the consumption of grapefruit and grapefruit juice during treatment with larotrectinib. Talk to your doctor or pharmacist if you have questions on this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Larotrectinib drug interactions
There are 511 drug interactions with larotrectinib.
Larotrectinib disease interactions
There is 1 disease interaction with larotrectinib which include:
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- Dosage information
- During pregnancy
- Drug class: multikinase inhibitors
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
