Isotretinoin Drug Interactions
Currently displaying a list of 142 drugs known to interact with isotretinoin.
- 24 major drug interactions
- 117 moderate drug interactions
- 1 minor drug interaction
Medications known to interact with isotretinoin
Note: Showing generic names only.
- abametapir topical
- abiraterone
- acitretin
- adagrasib
- adapalene topical
- alpelisib
- aminolevulinic acid
- aminolevulinic acid topical
- anisindione
- apalutamide
- asciminib
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- azelaic acid topical
- bedaquiline
- belzutifan
- benzoyl peroxide topical
- betamethasone
- bexarotene
- black cohosh
- brentuximab
- budesonide
- dabrafenib
- daclizumab
- daridorexant
- deflazacort
- demeclocycline
- dexamethasone
- dicumarol
- doxycycline
- drospirenone
- echinacea
- efavirenz
- enzalutamide
- epirubicin
- eravacycline
- ethanol
- etranacogene dezaparvovec
- etretinate
- leflunomide
- lemborexant
- lenacapavir
- letermovir
- levoketoconazole
- levonorgestrel
- lomitapide
- lonapegsomatropin
- lorlatinib
- mavacamten
- mavorixafor
- medroxyprogesterone
- methotrexate
- methoxsalen
- methyl aminolevulinate topical
- methylprednisolone
- mifepristone
- minocycline
- mipomersen
- mitapivat
- palovarotene
- pegaspargase
- peginterferon beta-1a
- pexidartinib
- phenytoin
- pirtobrutinib
- pitolisant
- porfimer
- pralsetinib
- prednisolone
- prednisone
- salicylic acid topical
- sarecycline
- selpercatinib
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotorasib
- sparsentan
- sulfur topical
- suzetrigine
- tazarotene topical
- tecovirimat
- telotristat
- teriflunomide
- tetracycline
- thioguanine
- thiotepa
- tigecycline
- trabectedin
- tretinoin
- tretinoin topical
- triamcinolone
- trifarotene topical
- trofinetide
Isotretinoin alcohol/food interactions
There are 3 alcohol/food interactions with isotretinoin.
Isotretinoin disease interactions
There are 5 disease interactions with isotretinoin which include:
- intracranial hypertension
- psychiatric disorders
- osteoporosis
- elevated serum triglycerides
- liver disease
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More about isotretinoin
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- During pregnancy
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- Drug class: miscellaneous antineoplastics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
