Sleepinal Interactions
There are 449 drugs known to interact with Sleepinal (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 15 are major, 431 are moderate, and 3 are minor.
- View all 449 medications that may interact with Sleepinal
- View Sleepinal alcohol/food interactions (1)
- View Sleepinal disease interactions (8)
Most frequently checked interactions
View interaction reports for Sleepinal (diphenhydramine) and the medicines listed below.
- Abilify (aripiprazole)
- acetaminophen / codeine
- Adderall XR (amphetamine / dextroamphetamine)
- Advil Dual Action (acetaminophen / ibuprofen)
- Aleve Back and Muscle Pain (naproxen)
- Allergy Sinus PE Pain Relief (acetaminophen / chlorpheniramine / phenylephrine)
- Ambien (zolpidem)
- Amitiza (lubiprostone)
- amitriptyline
- amlodipine
- amoxicillin
- Ativan (lorazepam)
- baclofen
- Bayer Aspirin (aspirin)
- ciprofloxacin
- dicyclomine
- duloxetine
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- Lasix (furosemide)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- metoprolol
- multivitamin
- spironolactone
- Vitamin B12 (cyanocobalamin)
- Wellbutrin (bupropion)
- zolpidem
Sleepinal alcohol/food interactions
There is 1 alcohol/food interaction with Sleepinal (diphenhydramine).
Sleepinal disease interactions
There are 8 disease interactions with Sleepinal (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
More about Sleepinal (diphenhydramine)
- Sleepinal consumer information
- Compare alternatives
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.