Sleepinal Interactions
There are 448 drugs known to interact with Sleepinal (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 14 are major, 432 are moderate, and 2 are minor.
- View all 448 medications that may interact with Sleepinal
- View Sleepinal alcohol/food interactions (1)
- View Sleepinal disease interactions (8)
Most frequently checked interactions
View interaction reports for Sleepinal (diphenhydramine) and the medicines listed below.
- Abilify (aripiprazole)
- acetaminophen / codeine
- Adderall XR (amphetamine / dextroamphetamine)
- Advil Dual Action (acetaminophen / ibuprofen)
- Aleve Back and Muscle Pain (naproxen)
- Allegra (fexofenadine)
- Ambien (zolpidem)
- Amitiza (lubiprostone)
- amitriptyline
- amlodipine
- amoxicillin
- ashwaganda
- Ativan (lorazepam)
- ciprofloxacin
- dicyclomine
- duloxetine
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- Lasix (furosemide)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- metoprolol
- multivitamin
- spironolactone
- sulfamethoxazole / trimethoprim
- Vitamin B12 (cyanocobalamin)
- Wellbutrin (bupropion)
- zolpidem
Sleepinal alcohol/food interactions
There is 1 alcohol/food interaction with Sleepinal (diphenhydramine).
Sleepinal disease interactions
There are 8 disease interactions with Sleepinal (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
More about Sleepinal (diphenhydramine)
- Sleepinal consumer information
- Compare alternatives
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.