Promethazine with Dextromethorphan Interactions
There are 752 drugs known to interact with Promethazine with Dextromethorphan (dextromethorphan / promethazine), along with 13 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 163 are major, 575 are moderate, and 14 are minor.
- View all 752 medications that may interact with Promethazine with Dextromethorphan
- View Promethazine with Dextromethorphan alcohol/food interactions (2)
- View Promethazine with Dextromethorphan disease interactions (13)
Most frequently checked interactions
View interaction reports for Promethazine with Dextromethorphan (dextromethorphan / promethazine) and the medicines listed below.
- acetaminophen
- acetaminophen / oxycodone
- albuterol
- Aspirin Low Strength (aspirin)
- atorvastatin
- azelastine nasal
- benzonatate
- bupropion
- cephalexin
- duloxetine
- Eliquis (apixaban)
- famotidine
- fluconazole
- folic acid
- furosemide
- gabapentin
- hydroxyzine
- ibuprofen
- levothyroxine
- lisinopril
- methocarbamol
- montelukast
- naproxen
- omeprazole
- pantoprazole
- prednisone
- rosuvastatin
- tramadol
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Promethazine with Dextromethorphan alcohol/food interactions
There are 2 alcohol/food interactions with Promethazine with Dextromethorphan (dextromethorphan / promethazine).
Promethazine with Dextromethorphan disease interactions
There are 13 disease interactions with Promethazine with Dextromethorphan (dextromethorphan / promethazine) which include:
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
Report options
More about Promethazine with Dextromethorphan (dextromethorphan / promethazine)
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.