Dextromethorphan/doxylamine Interactions
There are 427 drugs known to interact with dextromethorphan/doxylamine, along with 8 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 85 are major, 338 are moderate, and 4 are minor.
- View all 427 medications that may interact with dextromethorphan/doxylamine
- View dextromethorphan/doxylamine alcohol/food interactions (2)
- View dextromethorphan/doxylamine disease interactions (8)
Most frequently checked interactions
View interaction reports for dextromethorphan / doxylamine and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine)
- Aspirin Low Strength (aspirin)
- Atrovent (ipratropium)
- Azo Urinary Pain Relief (phenazopyridine)
- Benadryl (diphenhydramine)
- Calcium, Magnesium and Zinc (multivitamin with minerals)
- Celebrex (celecoxib)
- Chlorpheniramine (Allergy) (chlorpheniramine)
- Diflucan (fluconazole)
- Estroven (multivitamin with minerals)
- Excedrin Migraine (acetaminophen / aspirin / caffeine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Keflex (cephalexin)
- L-Arginine (arginine)
- Mucinex (guaifenesin)
- Mucus Relief (guaifenesin)
- Q-Sorb Co Q-10 (ubiquinone)
- Sporanox (itraconazole)
- Symbicort (budesonide / formoterol)
- Vitamin B12 (cyanocobalamin)
- Vitamin B6 (pyridoxine)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xyzal Allergy 24HR (levocetirizine)
- Zinc (zinc sulfate)
- Zinc-220 (zinc sulfate)
Dextromethorphan/doxylamine alcohol/food interactions
There are 2 alcohol/food interactions with dextromethorphan / doxylamine.
Dextromethorphan/doxylamine disease interactions
There are 8 disease interactions with dextromethorphan / doxylamine which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
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More about dextromethorphan / doxylamine
- dextromethorphan/doxylamine consumer information
- Compare alternatives
- Side effects
- Dosage information
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.