Clozaril Drug Interactions
Currently displaying a list of 946 drugs known to interact with Clozaril (clozapine).
- 528 major drug interactions
- 409 moderate drug interactions
- 9 minor drug interactions
Medications known to interact with Clozaril
Note: Showing generic names only.
A
- abametapir topical
- abarelix
- abemaciclib
- abiraterone
- abobotulinumtoxinA
- abrocitinib
- acalabrutinib
- acarbose
- acebutolol
- acetazolamide
- acetohexamide
- acetylcarbromal
- acetylcholine ophthalmic
- aclidinium
- acrivastine
- adagrasib
- adalimumab
- adenosine
- afamitresgene autoleucel
- albendazole
- albiglutide
- albuterol
- aldesleukin
- alefacept
- alemtuzumab
- alfentanil
- alfuzosin
- allopurinol
- alogliptin
- alprazolam
- altretamine
- amantadine
- ambenonium
- amifampridine
- amiloride
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amyl nitrite
- anagrelide
- anakinra
- anisindione
- anti-thymocyte globulin (rabbit)
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- aprocitentan
- arbutamine
- arformoterol
- aripiprazole
- armodafinil
- arsenic trioxide
- asciminib
- asenapine
- asparaginase escherichia coli
- astemizole
- atazanavir
- atenolol
- atomoxetine
- atropine
- auranofin
- aurothioglucose
- avapritinib
- axicabtagene ciloleucel
- azacitidine
- azatadine
- azathioprine
- azelastine nasal
- azilsartan medoxomil
- azithromycin
B
- baclofen
- baricitinib
- bedaquiline
- belantamab mafodotin
- belinostat
- belladonna
- benazepril
- bendamustine
- bendroflumethiazide
- benzgalantamine
- benzthiazide
- benztropine
- bepridil
- berotralstat
- betaxolol
- bethanechol
- bevacizumab
- bexagliflozin
- bexarotene
- bicalutamide
- bimekizumab
- biperiden
- bisacodyl
- bisoprolol
- bitolterol
- bleomycin
- blinatumomab
- bortezomib
- bosutinib
- brentuximab
- brexanolone
- brexpiprazole
- brexucabtagene autoleucel
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- brodalumab
- bromocriptine
- brompheniramine
- bumetanide
- buprenorphine
- bupropion
- buspirone
- busulfan
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabergoline
- cabozantinib
- caffeine
- canagliflozin
- canakinumab
- candesartan
- cannabidiol
- cannabis
- capecitabine
- capmatinib
- captopril
- carbachol ophthalmic
- carbamazepine
- carbetapentane
- carbinoxamine
- carboplatin
- carfilzomib
- cariprazine
- carisoprodol
- carmustine
- carteolol
- carvedilol
- casanthranol
- cascara sagrada
- castor oil
- celecoxib
- cenobamate
- ceritinib
- certolizumab
- cetirizine
- cevimeline
- chlophedianol
- chloral hydrate
- chlorambucil
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorpropamide
- chlorthalidone
- chlorzoxazone
- cilostazol
- ciltacabtagene autoleucel
- cimetidine
- cinacalcet
- ciprofloxacin
- cisapride
- cisplatin
- citalopram
- cladribine
- clarithromycin
- clemastine
- clevidipine
- clidinium
- clobazam
- clofarabine
- clofazimine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- cobicistat
- codeine
- colchicine
- copanlisib
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- cyclandelate
- cyclizine
- cyclobenzaprine
- cyclophosphamide
- cyproheptadine
- cytarabine
D
- dacarbazine
- dacomitinib
- dactinomycin
- dantrolene
- dapagliflozin
- dapsone
- daratumumab
- daridorexant
- darifenacin
- dasatinib
- daunorubicin
- daunorubicin liposomal
- daxibotulinumtoxinA
- decitabine
- deferasirox
- deferiprone
- degarelix
- demecarium bromide ophthalmic
- deserpidine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dexrazoxane
- dextromethorphan
- dezocine
- diazepam
- diazoxide
- dichlorphenamide
- dicumarol
- dicyclomine
- difelikefalin
- digitoxin
- diltiazem
- dimenhydrinate
- dinutuximab
- diphenhydramine
- disopyramide
- divalproex sodium
- docetaxel
- dofetilide
- dolasetron
- donepezil
- dopamine
- doxazosin
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drospirenone
- dulaglutide
- duloxetine
- duvelisib
E
- echinacea
- echothiophate iodide ophthalmic
- edrophonium
- efavirenz
- eflornithine
- eliglustat
- elotuzumab
- elranatamab
- eluxadoline
- emapalumab
- empagliflozin
- enalapril
- enalaprilat
- encorafenib
- enfortumab vedotin
- enoxacin
- entacapone
- entrectinib
- enzalutamide
- epcoritamab
- epinephrine
- epirubicin
- eplerenone
- eprosartan
- eribulin
- ertugliflozin
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- esmolol
- esomeprazole
- estazolam
- eszopiclone
- etanercept
- ethacrynic acid
- ethanol
- ethaverine
- ethchlorvynol
- ethinyl estradiol
- ethosuximide
- ethotoin
- etonogestrel
- etoposide
- etrasimod
- etravirine
- evening primrose
- exenatide
- ezogabine
F
- fam-trastuzumab deruxtecan
- famotidine
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fenofibrate
- fenoldopam
- fentanyl
- fesoterodine
- fexinidazole
- fingolimod
- flavoxate
- flecainide
- flibanserin
- floxuridine
- fluconazole
- flucytosine
- fludarabine
- fluorouracil
- fluoxetine
- fluphenazine
- flurazepam
- flutamide
- fluvoxamine
- formoterol
- foscarnet
- fosinopril
- fosphenytoin
- fostamatinib
- fostemsavir
- furosemide
G
- gabapentin
- gabapentin enacarbil
- galantamine
- ganaxolone
- ganciclovir
- gatifloxacin
- gemcitabine
- gemifloxacin
- gemtuzumab
- gepirone
- gilteritinib
- ginkgo
- givinostat
- givosiran
- glasdegib
- glimepiride
- glipizide
- glofitamab
- glyburide
- glycerin
- glycerol phenylbutyrate
- glycopyrrolate
- glycopyrronium topical
- gold sodium thiomalate
- golimumab
- goserelin
- granisetron
- grepafloxacin
- guanabenz
- guanadrel
- guanethidine
- guanfacine
- guanidine
- guselkumab
H
- halazepam
- halofantrine
- haloperidol
- halothane
- heroin
- histrelin
- hydralazine
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyurea
- hydroxyzine
- hyoscyamine
I
- ibritumomab
- ibrutinib
- ibutilide
- idarubicin
- idecabtagene vicleucel
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imetelstat
- imipramine
- inavolisib
- incobotulinumtoxinA
- indacaterol
- indapamide
- infliximab
- inotuzumab ozogamicin
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- interferon alfa-2a
- interferon alfa-2b
- interferon alfa-n1
- interferon alfacon-1
- interferon gamma-1b
- iobenguane I 131
- iodine i 131 tositumomab
- ioflupane I 123
- iohexol
- iomeprol
- iopamidol
- ipratropium
- ipratropium nasal
- irbesartan
- irinotecan
- irinotecan liposomal
- isatuximab
- isocarboxazid
- isoetharine
- isoflurophate ophthalmic
- isoproterenol
- isosorbide
- isosorbide dinitrate
- isosorbide mononitrate
- isoxsuprine
- isradipine
- ivabradine
- ivosidenib
- ixabepilone
- ixazomib
K
L
- labetalol
- lactitol
- lactulose
- lamotrigine
- landiolol
- lapatinib
- lasmiditan
- lefamulin
- leflunomide
- lemborexant
- lenalidomide
- leniolisib
- lenvatinib
- letibotulinumtoxinA
- leuprolide
- levalbuterol
- levamisole
- levamlodipine
- levetiracetam
- levocetirizine
- levodopa
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levonorgestrel
- levorphanol
- lidocaine
- lifileucel
- linagliptin
- lindane topical
- linezolid
- liraglutide
- lisdexamfetamine
- lisinopril
- lisocabtagene maraleucel
- lithium
- lixisenatide
- lofexidine
- lomefloxacin
- lomustine
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- loperamide
- lorazepam
- lorcaserin
- losartan
- loxapine
- lumateperone
- lurasidone
- lurbinectedin
- lutetium lu 177 dotatate
- lutetium lu 177 vipivotide tetraxetan
- lymphocyte immune globulin, anti-thy (equine)
M
- macimorelin
- magnesium citrate
- magnesium hydroxide
- maprotiline
- mavacamten
- mavorixafor
- mecamylamine
- mechlorethamine
- meclizine
- medroxyprogesterone
- mefloquine
- melatonin
- melphalan
- melphalan flufenamide
- mepenzolate
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mercaptopurine
- mesoridazine
- metaproterenol
- metaxalone
- metformin
- methadone
- methazolamide
- methdilazine
- methimazole
- methocarbamol
- methohexital
- methotrexate
- methotrimeprazine
- methscopolamine
- methsuximide
- methyclothiazide
- methyldopa
- metoclopramide
- metolazone
- metoprolol
- metrizamide
- metronidazole
- mibefradil
- midazolam
- midostaurin
- mifepristone
- miglitol
- milnacipran
- mineral oil
- minoxidil
- mirabegron
- mirtazapine
- mitomycin
- mitotane
- mitoxantrone
- mobocertinib
- modafinil
- moexipril
- mogamulizumab
- molindone
- momelotinib
- morphine
- morphine liposomal
- mosunetuzumab
- moxetumomab pasudotox
- moxifloxacin
- mycophenolate mofetil
- mycophenolic acid
N
- nabilone
- nadolol
- nalbuphine
- nalidixic acid
- nateglinide
- naxitamab
- nebivolol
- nefazodone
- nelarabine
- nemolizumab
- neostigmine
- niacin
- nicardipine
- nicotinamide
- nicotine
- nifedipine
- nilotinib
- nilutamide
- nimodipine
- niraparib
- nisoldipine
- nitroglycerin
- nitroprusside
- norethindrone
- norfloxacin
- norgestrel
- nortriptyline
O
- obecabtagene autoleucel
- obeticholic acid
- obinutuzumab
- ofatumumab
- ofloxacin
- olanzapine
- olaparib
- olaratumab
- oliceridine
- olmesartan
- olodaterol
- olopatadine nasal
- olutasidenib
- omacetaxine
- omaveloxolone
- omeprazole
- onabotulinumtoxinA
- ondansetron
- opicapone
- opium
- oritavancin
- orphenadrine
- osilodrostat
- osimertinib
- oxaliplatin
- oxazepam
- oxcarbazepine
- oxybutynin
- oxycodone
- oxymorphone
- oxytocin
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- paraldehyde
- paramethadione
- paroxetine
- pasireotide
- pazopanib
- pegaspargase
- peginterferon alfa-2a
- peginterferon alfa-2b
- pemetrexed
- penbutolol
- penicillamine
- pentamidine
- pentazocine
- pentobarbital
- pentostatin
- perampanel
- perflutren
- pergolide
- perindopril
- perphenazine
- phenacemide
- phenelzine
- phenindamine
- phenobarbital
- phenolphthalein
- phenoxybenzamine
- phensuximide
- phentolamine
- phenylbutazone
- phenytoin
- physostigmine
- physostigmine ophthalmic
- pilocarpine
- pilocarpine ophthalmic
- pimavanserin
- pimozide
- pindolol
- pioglitazone
- pirbuterol
- pirtobrutinib
- pitolisant
- plicamycin
- polatuzumab vedotin
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- polythiazide
- pomalidomide
- ponatinib
- ponesimod
- porfimer
- posaconazole
- potassium chloride
- potassium citrate
- prabotulinumtoxinA
- pralatrexate
- pralsetinib
- pramipexole
- pramlintide
- prazosin
- pregabalin
- primaquine
- primidone
- probucol
- procainamide
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propafenone
- propantheline
- propiomazine
- propofol
- propoxyphene
- propranolol
- propylthiouracil
- protriptyline
- pyridostigmine
- pyrilamine
Q
R
- radium 223 dichloride
- ramelteon
- ramipril
- ranolazine
- rasagiline
- rauwolfia serpentina
- relugolix
- remifentanil
- remimazolam
- repaglinide
- reserpine
- revefenacin
- revumenib
- ribociclib
- rifabutin
- rifampin
- rilonacept
- rilpivirine
- rimabotulinumtoxinB
- risperidone
- ritlecitinib
- ritodrine
- ritonavir
- rituximab
- rivastigmine
- rizatriptan
- rolapitant
- romidepsin
- ropeginterferon alfa-2b
- ropinirole
- rosiglitazone
- rotigotine
- rucaparib
- rufinamide
- ruxolitinib
S
- sacituzumab govitecan
- safinamide
- salmeterol
- samarium sm 153 lexidronam
- saquinavir
- sarilumab
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- satralizumab
- saxagliptin
- scopolamine
- secobarbital
- secukinumab
- selegiline
- selinexor
- selpercatinib
- semaglutide
- senna
- sertraline
- sevoflurane
- sibutramine
- siltuximab
- siponimod
- sirolimus protein-bound
- sitagliptin
- sodium oxybate
- sodium phosphate p32
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotagliflozin
- sotalol
- sparfloxacin
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- streptozocin
- strontium-89 chloride
- sufentanil
- sulfadiazine
- sulfamethoxazole
- sunitinib
- suvorexant
T
- tacrine
- tacrolimus
- tafasitamab
- tagraxofusp
- talazoparib
- talquetamab
- tamoxifen
- tapentadol
- tarlatamab
- tasimelteon
- tazemetostat
- tebentafusp
- teclistamab
- telavancin
- telithromycin
- telmisartan
- temazepam
- temozolomide
- teniposide
- terazosin
- terbinafine
- terbutaline
- terfenadine
- teriflunomide
- tetrabenazine
- thalidomide
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thiotepa
- thiothixene
- tiagabine
- ticlopidine
- timolol
- tiotropium
- tirzepatide
- tisagenlecleucel
- tisotumab vedotin
- tizanidine
- tocainide
- tocilizumab
- tofacitinib
- tolazamide
- tolazoline
- tolbutamide
- tolcapone
- tolterodine
- topiramate
- topotecan
- toremifene
- torsemide
- tositumomab
- trabectedin
- tramadol
- trandolapril
- tranylcypromine
- trastuzumab
- trazodone
- treosulfan
- triamterene
- triazolam
- trichlormethiazide
- triclabendazole
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethaphan camsylate
- trimethobenzamide
- trimetrexate
- trimipramine
- tripelennamine
- triprolidine
- triptorelin
- trofinetide
- troglitazone
- troleandomycin
- trospium
U
V
- valbenazine
- valerian
- valganciclovir
- valproic acid
- valsartan
- vandetanib
- vardenafil
- varenicline
- vasopressin
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vigabatrin
- viloxazine
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- voriconazole
- vorinostat
W
Z
- zaleplon
- zanidatamab
- zanubrutinib
- ziconotide
- zidovudine
- ziprasidone
- ziv-aflibercept
- zolbetuximab
- zolpidem
- zonisamide
- zuranolone
Clozaril alcohol/food interactions
There are 4 alcohol/food interactions with Clozaril (clozapine).
Clozaril disease interactions
There are 20 disease interactions with Clozaril (clozapine) which include:
- dementia
- agranulocytosis
- anticholinergic effects
- hepatitis
- acute alcohol intoxication
- CNS depression
- NMS
- aspiration
- seizure
- hyperglycemia/diabetes
- hypotension
- lipid alterations
- weight gain
- hyperglycemia
- renal dysfunction
- thromboembolic events
- hyperprolactinemia
- liver disease
- parkinsonism
- tardive dyskinesia
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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