Zynrelef Interactions
There are 578 drugs known to interact with Zynrelef (bupivacaine/meloxicam), along with 13 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 121 are major, 407 are moderate, and 50 are minor.
- View Zynrelef alcohol/food interactions (2)
- View Zynrelef disease interactions (13)
Medications known to interact with Zynrelef
Note: Showing generic names only.
A
- abametapir topical
- abciximab
- abiraterone
- abrocitinib
- acalabrutinib
- acebutolol
- acetaminophen
- acetohexamide
- adagrasib
- adefovir
- ado-trastuzumab emtansine
- alemtuzumab
- alendronate
- alfentanil
- aliskiren
- alpelisib
- alprazolam
- alteplase
- ambenonium
- amikacin
- amikacin liposome
- amiloride
- aminosalicylic acid
- amiodarone
- amlodipine
- amprenavir
- amyl nitrite
- anagrelide
- anisindione
- anistreplase
- antithrombin (recombinant)
- antithrombin iii
- apalutamide
- apixaban
- aprepitant
- aprocitentan
- ardeparin
- argatroban
- asciminib
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- aspirin
- atazanavir
- atenolol
- atovaquone
- atracurium
- avapritinib
- azilsartan medoxomil
B
- balsalazide
- baricitinib
- bedaquiline
- benazepril
- bendroflumethiazide
- benoxinate ophthalmic
- benzgalantamine
- benzocaine topical
- benzthiazide
- bepridil
- berotralstat
- betamethasone
- betaxolol
- betaxolol ophthalmic
- betiatide
- betrixaban
- bisoprolol
- bivalirudin
- black cohosh
- boceprevir
- bosentan
- botulism immune globulin
- brentuximab
- bretylium
- bromfenac
- budesonide
- bumetanide
- bupivacaine liposome
C
- cabozantinib
- calaspargase pegol
- candesartan
- cangrelor
- cannabidiol
- caplacizumab
- captopril
- carteolol
- carteolol ophthalmic
- carvedilol
- celecoxib
- ceritinib
- chloramphenicol
- chlordiazepoxide
- chloroprocaine
- chloroprocaine ophthalmic
- chloroquine
- chlorothiazide
- chlorpropamide
- chlorthalidone
- cholestyramine
- cidofovir
- cilostazol
- cimetidine
- cinoxacin
- ciprofloxacin
- cisatracurium
- citalopram
- clarithromycin
- clobazam
- clofarabine
- clofazimine
- clomipramine
- clonazepam
- clopidogrel
- clorazepate
- clove
- cobicistat
- cocaine nasal
- cocaine topical
- conivaptan
- cortisone
- crizotinib
- cyclophosphamide
- cyclosporine
- cytomegalovirus immune globulin
D
- dabigatran
- dabrafenib
- daclizumab
- dalteparin
- danaparoid
- daprodustat
- dapsone
- dapsone topical
- daptomycin
- darunavir
- dasatinib
- deferasirox
- defibrotide
- deflazacort
- delafloxacin
- delavirdine
- desipramine
- desirudin
- desmopressin
- desvenlafaxine
- dexamethasone
- dexfenfluramine
- diatrizoate
- diazepam
- dibucaine topical
- diclofenac
- diclofenac topical
- dicumarol
- diflunisal
- digoxin
- diltiazem
- dimethyl fumarate
- dipyridamole
- diroximel fumarate
- disopyramide
- divalproex sodium
- dofetilide
- donepezil
- doxacurium
- dronedarone
- drospirenone
- drotrecogin alfa
- duloxetine
- duvelisib
E
- edoxaban
- edrophonium
- efavirenz
- enalapril
- enalaprilat
- enoxacin
- enoxaparin
- entecavir
- enzalutamide
- epirubicin
- eplerenone
- epoprostenol
- eprosartan
- eptifibatide
- erlotinib
- erythromycin
- escitalopram
- esmolol
- estazolam
- ethacrynic acid
- ethanol
- etidocaine
- etidronate
- etodolac
- etranacogene dezaparvovec
- etrasimod
- etravirine
- everolimus
- exenatide
F
- famotidine
- fedratinib
- felodipine
- fenfluramine
- fenofibrate
- fenofibric acid
- fenoprofen
- fexinidazole
- fidanacogene elaparvovec
- flecainide
- fluconazole
- flucytosine
- fludrocortisone
- fluoxetine
- flurazepam
- flurbiprofen
- flutamide
- fluvoxamine
- fondaparinux
- fosamprenavir
- fosaprepitant
- fosinopril
- furosemide
G
- galantamine
- ganciclovir
- gatifloxacin
- gemfibrozil
- gemifloxacin
- gentamicin
- ginkgo
- glimepiride
- glipizide
- glyburide
- grepafloxacin
- guanidine
H
- halazepam
- heparin
- heparin flush
- horse chestnut
- house dust mite allergen extract
- hyaluronidase
- hydralazine
- hydrochlorothiazide
- hydrocortisone
- hydroflumethiazide
- hydroxyurea
I
- ibandronate
- ibritumomab
- ibrutinib
- ibuprofen
- ibutilide
- icosapent
- idelalisib
- ifosfamide
- iloprost
- imatinib
- immune globulin intravenous
- immune globulin intravenous and subcutaneous
- indapamide
- indinavir
- indomethacin
- inotersen
- interferon beta-1a
- interferon beta-1b
- iodamide
- iodine i 131 tositumomab
- iodipamide
- iodixanol
- iohexol
- iomeprol
- iopamidol
- iopromide
- iothalamate
- ioversol
- ioxaglate
- ioxilan
- irbesartan
- isavuconazonium
- isoniazid
- isosorbide
- isosorbide dinitrate
- isosorbide mononitrate
- isradipine
- itraconazole
- ivacaftor
- ivosidenib
K
L
- labetalol
- landiolol
- lefamulin
- leflunomide
- lenacapavir
- lepirudin
- letermovir
- levamlodipine
- levobetaxolol ophthalmic
- levobunolol ophthalmic
- levobupivacaine
- levofloxacin
- levoketoconazole
- levomilnacipran
- lidocaine
- lidocaine ophthalmic
- lidocaine otic
- lidocaine topical
- linaclotide
- lisinopril
- lithium
- lomefloxacin
- lomitapide
- lonafarnib
- lorazepam
- lorlatinib
- losartan
- lvp solution with potassium
M
- macimorelin
- mafenide topical
- mavacamten
- meclofenamate
- mefenamic acid
- meperidine
- mepivacaine
- mesalamine
- metformin
- methotrexate
- methoxyflurane
- methyclothiazide
- methylprednisolone
- metipranolol ophthalmic
- metoclopramide
- metocurine
- metolazone
- metoprolol
- metrizamide
- metronidazole
- mexiletine
- mibefradil
- miconazole
- midazolam
- mifepristone
- milnacipran
- mipomersen
- mitapivat
- mivacurium
- mixed grass pollens allergen extract
- moexipril
- monomethyl fumarate
- moricizine
- morphine liposomal
- moxifloxacin
N
- nabumetone
- nadolol
- nalidixic acid
- naltrexone
- naproxen
- nateglinide
- nebivolol
- nefazodone
- nelfinavir
- neostigmine
- netilmicin
- nicardipine
- nifedipine
- nilotinib
- nimodipine
- nintedanib
- niraparib
- nirogacestat
- nisoldipine
- nitisinone
- nitric oxide
- nitrofurantoin
- nitroglycerin
- nitroprusside
- nitrous oxide
- nizatidine
- norfloxacin
O
- ofloxacin
- olmesartan
- olsalazine
- omacetaxine
- omega-3 polyunsaturated fatty acids
- oritavancin
- oxaliplatin
- oxandrolone
- oxaprozin
- oxazepam
P
- pamidronate
- pancuronium
- panobinostat
- paroxetine
- peanut allergen powder
- pegaspargase
- peginterferon beta-1a
- pemetrexed
- penbutolol
- pentoxifylline
- perindopril
- pexidartinib
- phenazopyridine
- phenobarbital
- phenylbutazone
- phenytoin
- physostigmine
- pindolol
- pipecuronium
- piroxicam
- pitolisant
- plasminogen, human
- plazomicin
- polyethylene glycol 3350 with electrolytes
- polythiazide
- ponatinib
- posaconazole
- potassium acid phosphate
- potassium aminobenzoate
- potassium bicarbonate
- potassium chloride
- potassium citrate
- potassium gluconate
- potassium iodide
- potassium perchlorate
- potassium phosphate
- pralatrexate
- pralsetinib
- pramoxine topical
- prasugrel
- prazosin
- prednisolone
- prednisone
- prilocaine
- primaquine
- probenecid
- procainamide
- procaine
- procaine penicillin
- propafenone
- proparacaine ophthalmic
- propranolol
- pyridostigmine
Q
R
- ragweed pollen allergen extract
- ramipril
- ramucirumab
- ranitidine
- ranitidine bismuth citrate
- rapacuronium
- rasburicase
- regorafenib
- remdesivir
- remimazolam
- repaglinide
- respiratory syncytial virus immune globulin
- reteplase
- revakinagene taroretcel
- rho (d) immune globulin
- ribociclib
- rifampin
- rifapentine
- risedronate
- ritlecitinib
- ritonavir
- rivaroxaban
- rivastigmine
- rocuronium
- rofecoxib
- ropivacaine
- rucaparib
- ruxolitinib
S
- saquinavir
- sertraline
- sibutramine
- silver nitrate topical
- silver sulfadiazine topical
- sirolimus
- sodium nitrite
- sodium polystyrene sulfonate
- sotalol
- sparfloxacin
- sparsentan
- spironolactone
- stiripentol
- streptokinase
- streptomycin
- succinylcholine
- sulfadiazine
- sulfamethizole
- sulfamethoxazole
- sulfasalazine
- sulfinpyrazone
- sulfisoxazole
- sulindac
T
- tacrine
- tacrolimus
- tafasitamab
- tafenoquine
- tamoxifen
- tazemetostat
- telaprevir
- telbivudine
- telithromycin
- telmisartan
- temazepam
- temsirolimus
- tenecteplase
- tenofovir alafenamide
- tenofovir disoproxil
- teriflunomide
- tetracaine
- tetracaine ophthalmic
- tetracaine topical
- thioguanine
- ticagrelor
- ticlopidine
- tilmanocept
- tiludronate
- timolol
- timolol ophthalmic
- timothy grass pollen allergen extract
- tinzaparin
- tirofiban
- tobramycin
- tocainide
- tofacitinib
- tolazamide
- tolbutamide
- tolmetin
- toremifene
- torsemide
- tositumomab
- tovorafenib
- trabectedin
- trandolapril
- trazodone
- treprostinil
- triamcinolone
- triamcinolone ophthalmic
- triamterene
- triazolam
- trichlormethiazide
- trimethoprim
- troleandomycin
- trospium
- trovafloxacin
- tubocurarine
- tucatinib
- turmeric
U
V
- vadadustat
- valacyclovir
- valdecoxib
- valganciclovir
- valoctocogene roxaparvovec
- valproic acid
- valsartan
- vamorolone
- vancomycin
- vasopressin
- vecuronium
- venlafaxine
- verapamil
- verteporfin
- vilazodone
- vismodegib
- voclosporin
- vorapaxar
- voriconazole
- vortioxetine
- voxelotor
W
Z
Zynrelef alcohol/food interactions
There are 2 alcohol/food interactions with Zynrelef (bupivacaine / meloxicam).
Zynrelef disease interactions
There are 13 disease interactions with Zynrelef (bupivacaine / meloxicam) which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- cardiovascular disease
- liver disease
- renal impairment
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
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More about Zynrelef (bupivacaine / meloxicam)
- Zynrelef consumer information
- Compare alternatives
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- Reviews (1)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: analgesic combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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