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Epiduo (adapalene / benzoyl peroxide topical) Drug Interactions

A total of 19 drugs are known to interact with Epiduo (adapalene / benzoyl peroxide topical).

  • 6 moderate drug interactions
  • 13 minor drug interactions

Check for interactions with Epiduo (adapalene / benzoyl peroxide topical)

Type in a drug name and select a drug from the list.

Medications known to interact with Epiduo (adapalene / benzoyl peroxide topical)

  • ammoniated mercury / salicylic acid topical (Emersal)
  • benzoic acid / salicylic acid topical (Whitfields Ointment)
  • benzoyl peroxide / salicylic acid topical (Inova 8/2, Cleanse & Treat Plus, Cleanse & Treat, BeyondClear, Inova 4/1)
  • clindamycin / tretinoin topical (Veltin, Ziana)
  • coal tar / lactic acid / salicylic acid topical (SLT)
  • coal tar / salicylic acid topical (X-Seb T Pearl, X-Seb T Plus)
  • coal tar / salicylic acid / sulfur topical (Sebutone, Ala Seb T, Pazol XS)
  • dapsone topical (Aczone)
  • doxycycline / salicylic acid topical (Avidoxy DK)
  • fluocinolone / hydroquinone / tretinoin topical (Tri-Luma)
  • hydrocortisone / salicylic acid / sulfur topical (Scalacort DK, Coraz)
  • isotretinoin (Accutane, Claravis, Myorisan, Absorica, Amnesteem, Sotret, Zenatane)
  • mequinol / tretinoin topical (Solage)
  • pyrithione zinc / salicylic acid topical (X-Seb Plus)
  • salicylic acid topical (Compound W, Wart Remover, Duofilm, Salex, Bensal HP, Salicylic Acid Cleansing Bar, Herbal Essences Anti-Dandruff Shampoo, Psoriasin Medicated Wash, Dermarest Psoriasis Skin Treatment, Durasal, Trans-Ver-Sal, Acnex, Salac, P & S, T/Gel, Tinamed Plantar, Salvax, Dr Scholl's Corn/Callous Remover, Freezone, Salacyn, Acne and Blemish Target, Let Me Clarify Gel, Panscol, Dr Scholl's Clear Away Wart Remover, Off-Eazy, Dr Scholl's Corn Removers, Maximum Strength Wart Remover, Dr Scholl's OneStep Callus Removers, Gordofilm, Dr Scholl's OneStep Corn Removers, Salactic Film, Dr Scholl's Callus Removers, Mosco Corn & Callus Remover, Dr Scholl's Corn/Callus Remover, Mosco-Cain, Dr Scholl's Corn Removers Small, Dr Scholl's Corn Removers Ultra-Thin, Sal-Plant Gel, Dr Scholl's Corn Removers Extra Thick, Sal-Acid Plasters, Mediplast, DHS Salicylic Acid 3%, Acnomel Acne Mask, Ionil Shampoo, Wart-Off Treatment, Bioelements Active Astringent, Wart Away, Ionil Plus, Stri-Dex, Neutrogena Healthy Scalp, Stri-Dex Sensitive Skin, Xalix, Fostex, Stridex Body Focus, Stri-Dex Clear Gel, Hydrisalic, Stri-Dex Face Wash, Stri-Dex Dual Textured, Duoplant, Stri-Dex Super Scrub, Sebucare, Neutrogena Acne Wash Oil Free, Neutrogena Healthy Scalp Dandruff Shampoo, X-Seb, Propa P.H., CeraVe SA Renewing, Propa PH Maximum Strength, Propa PH Foaming Face Wash, Oxy Clean Medicated, Oxy Clean Maximum Strength, Oxy Nightwatch Maximum Strength, Clear Away Wart Removal System, ACNE FIGHTING FOUNDATION, Propa PH Acne Mask, ACNE FIGHTING ROLL ON GEL, Propa PH Skin Cleanser Normal/Sensitive, Acne Lab Foam Cleanser, Gets-It Corn and Callus Remover, Sebasorb, Adasept Acne, Acne Off Acne Treatment, Neostrata Astringent Acne Treatment, Acne Off Acne Treatment Facial, Derma Controle: Nettoyant Moussant, Acne Solution, Derma Controle: Normalisant, ACNE SOLUTIONS CLARIFYING, Derma Controle: Purifiante, ACNE SOLUTIONS CLEANSING BAR FOR FACE AND BODY, Trans-Plantar, Acne Solutions Cleansing Foam, Freezeone One Step, Acne Solution Clearing Concealer Acne Medication All Skin Types, Acnisal, Keralyt Shampoo, Clinique Acne Solutions Oil Control Cleansing Mask, Bazuka Extra Strength, Verrugon Complete, Wartex, Yat Tip Xiao Corn and Callus Removing Plaster, Clean & Clear Blackhead Clearing Scrub, Yes To Tomatoes Acne Fighting Body Wash, Clean & Clear Concealing Treatment, Yes To Tomatoes Acne Fighting Paper Mask, Clear Logix Deep Cleansing Acne Treatment, Yes To Tomatoes Acne Clearing Facial Toner, Clear Logix Gentle Foaming Facial Cleanser, Yes To Tomatoes Clear Skin Corrective Concealer Light Tint, Clear Logix Sensitive Skin Astringent, Yes To Tomatoes Daily Repair Treatment, Clearasil Acne Fighting, Yes To Tomatoes Detoxifying Charcoal Cleanser, Clearasil Ice Wash, Yes To Tomatoes Detoxifying Charcoal Mud Mask, Clearasil Overnight Defense, UltraSal-ER, Clinique Acne Solutions Quick Clearing, Clinique Acne Solutions Spot Treatment, YS Solution Ac Care, Denorex Extra Strength Protection, YS Solution Ac Control Skin Regular Mild, Clear Logix Acne Spot Treatment, YS Solution Intensive AC Care, Clear Logix Oil Fighting Daily Wash, Clear Logix Oily Skin Astringent, Clearasil 3-In-1 Cleanser, Clearasil Stayclear Deep Clean Astringent, Aliclen, Stri-Dex Maximum Strength, Clearasil Stayclear Deep Clean Pad, Stridex Naturally Clear, Clinique Acne Solutions Body Treatment, Clinique Acne Solutions Concealing, Selsun Blue Deep Cleansing, Biore Blemish Undercover Agent, Selsun Blue Naturals Island Breeze, Phisoderm Acne Mask, Selsun Blue Naturals Itchy Dry Scalp, Neutrogena Soothing Astringent, Acnevir Facial Wash, Neutrogena T/Gel Conditioner, Clearasil Total Control Daily, Clearasil Total Control Deep Pore Cleanser, Salkera, Clearasil Blackhead Clearing Pads, Oxy Triple Action, Propa pH Acne Med Cleansing, Phisoderm Acne Therapy, Stridex Maximum Strength, Neutrogena Healthy Scalp Antidandruff, Dr Scholl's Zino Soft Corn Remover, Neutrogena Clear Pore Treatment, Neutrogena Clear Pore Oil Absorbing, Psoriasin Therapeutic Shampoo & Body Wash, Clean & Clear Dual Action, Oxy Balance Deep Pore Cleansing, Gentle, Oxy Balance Deep Pore Cleansing, Maximum, Thera-Sal, Oxy Balance Daily Cleaning, Normal Skin, H2O Acne Spot Treatment, Neutrogena T/Sal, Phytum Antipelliculaire Shampooing Purifiant, Dermarest Psoriasis Overnight Treatment, KeralytGel, Dermarest Psoriasis Shampoo Plus Conditioner, Dermarest Psoriasis Medicated Moisturizer, Oxy Daily Cleansing, Oxy Face Scrub Chill Factor, Oxy Face Scrub, Freezone Corn Remover, Akurza, Scalpicin Scalp Relief, Salitop, Denorex Medicated Balanced Strength, Salex Cream, DermalZone, Clear Up Prep, Oxy Balance Deep Pore Cleanser, Propa pH Acne Med Maximum Strength, Occlusal-HP, Keralyt Scalp, Acnevir, Acne & Oil Control, Acne Astringent Toner Pads, Acne Solutions Cleansing Gel, Acne Cleansing Pads, Acne Cleansing Wipes, Virasal)
  • salicylic acid / sodium thiosulfate topical (Versiclear, Exoderm)
  • salicylic acid / sulfur topical (Fostex Medicated, Sebex, Fostex Medicated Cleansing Cream, Sebulex Shampoo and Conditioner, Sebulex Shampoo, Pernox Lotion, Pernox Regular, Pernox Lemon, Fostex Medicated Cleaning Bar, Sastid Soap, Meted, Sebulex, Pernox Scrub Cleanser, Pernox, SAStid, Ala Seb)
  • salicylic acid / urea topical (Salvax Duo Plus, Kerasal, Carb-O-Sal5, Salvax Duo)
  • tretinoin topical (Retin-A, Renova, Atralin, Avita, Retin A Micro, Refissa, Tretin-X, Stieva-A, Retin-A and Renova, Obagi, Altreno, Retisol-A, Vitinoin, Altinac, Stieva-A Forte)

Epiduo (adapalene / benzoyl peroxide topical) disease interactions

There are 2 disease interactions with Epiduo (adapalene / benzoyl peroxide topical) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.