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Actifed Cold and Sinus (acetaminophen / pseudoephedrine / triprolidine) Drug Interactions

A total of 981 drugs are known to interact with Actifed Cold and Sinus (acetaminophen / pseudoephedrine / triprolidine).

  • 187 major drug interactions
  • 747 moderate drug interactions
  • 47 minor drug interactions

Show all medications in the database that may interact with Actifed Cold and Sinus (acetaminophen / pseudoephedrine / triprolidine).

Check for interactions

Type in a drug name to check for interactions with Actifed Cold and Sinus (acetaminophen / pseudoephedrine / triprolidine).

Most frequently checked interactions

View interaction reports for Actifed Cold and Sinus (acetaminophen / pseudoephedrine / triprolidine) and the medicines listed below.

  • Advil (ibuprofen)
  • calcium citrate (Calcitrate, Citracal Kosher)
  • cyclosporine (Neoral, Sandimmune, Gengraf)
  • Cymbalta (duloxetine)
  • docusate (Colace, DOK, Dulcolax Stool Softener, Doc-Q-Lace, DSS, Surfak, Docuprene, Silace, Enemeez Mini, Colace Micro-Enema, Doculase, Docu, Docusoft S, Calcium Stool Softener, Calube, Octycine-250, Phillips Stool Softener, DocuSol, Pedia-Lax Stool Softener, Promolaxin, Docusil, Diocto, Dialose, Surfak Stool Softener, DC-240, Kasof, Sulfalax Calcium, DOS, Modane Soft, Regulax SS, Dioeze, Aqualax, Dioctocal, Dioctosoftez, Dioctyn, Dionex, Docu Soft, Docucal, D-S Caps, Ex-Lax Stool Softener, Genasoft, Sur-Q-Lax, Doss-Relief, Fleet Sof-Lax Stool Softener, Correctol Softgel Extra Gentle, Therevac-SB, Octycine-100, Sulfolax, Kaopectate Stool Softener, Kao-Tin, Pedia-Lax Liquid Stool Softener, Vacuant, DocuSol Kids)
  • eszopiclone (Lunesta)
  • Evista (raloxifene)
  • FiberCon (polycarbophil)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Motrin IB, Proprinal, Advil Children's, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Motrin Childrens, Rufen, Ibuprofen PMR, Ibu-8, Motrin Pediatric, Menadol, Nuprin, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Advil Migraine, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, NeoProfen, Ibu-Tab, Genpril, Haltran, IBU-200, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • lorazepam (Ativan, Lorazepam Intensol)
  • multivitamin with minerals (Centrum, Centrum Silver, Ocuvite, PreserVision, PreserVision AREDS 2, Ocuvite Lutein, Flintstones Complete, Emergen-C, Airborne, Strovite, Calcium 600+D Plus Minerals, Centrum Adults, ICaps AREDS, Certa-Vite Senior Plus Lutein, Theragran-M, Cerovite Advanced Formula, Nicotinamide ZCF, Flintstones Gummies, ProRenal QD, Folgard, Nicadan, Tandem Plus, Viactiv Calcium Flavor Glides, AquADEKs, Therems M, I-Vite, Multilex, Vitamin C plus Zinc, Thera-M, Antioxidant Formula, Vitafol, Renax, Nicomide, Zincvit, Airborne Everyday, Recal D, Gevrabon, Centratex, Macular Health Formula, Celebrate Calcium Plus 500, Certa-Vite, Central, Antioxid Caplets, Prosight, Calcium Magnesium Potassium, Dolomite, Caltrate Plus, Thyrosol, Theragener-M, Vol-Plus, Prosteon, Actiflovit, Spectravite Cardio Health, Certavite, Geritol Complete, Support, Ocuvite PreserVision, Siderol, MagneBind 400 Rx, Caltrate 600+D Plus Minerals, Hemax, ICaps MV, Viactiv Multi-Vitamin, Abatron, Multi-Day Plus Minerals, RenaPlex, Caltrate 600 Plus, AquADEKs Pediatric, elon Matrix 5000 Complete, V-C Forte, Centamin, Vitacon Forte, Betamed, Fosfree, ChoiceFul, Rx Support Heartburn and Acid Reflux, CalMag Thins, Advanced AM/PM, Sesame St Vitamins Complete, Central-Vite, MultiVitamin Plus Zinc, One-A-Day Vitacraves, Centrum Silver Men's, Apetigen-Plus, Bladder 2.2, Essentia, Strovite One, TheraLith XR, Flintstones with Calcium, Z-Bec, Daily Multiple for Women, Hair Booster, Macular Vitamin Benefit, SSS, Multilex-T/M+Minerals, Centrum Cardio, RenaPlex-D, CertaVite with Lutein, Cerovite Junior, ABDEK, Corvita, Vitamax, ICaps with Lutein and Zeaxan, Viactiv Soft Calcium Chews, Hemocyte Plus, DermaVite, CertaVite with Antioxidants, Hematinic Plus, Centrum Performance, Daily Multi-Vitamins with Minerals, Occuplex, NicAzel, MaxFe, DEKAs Plus, Nicaprin, Lipoflavovit, Ocuvite Eye + Multi, Somnicin, Nutricap, Calafol Rx, Corvite, Ostiva, ProRenal Vital, Centrum Kids, Spectravite Senior, Centrum Ultra Men's, Centrum Silver Ultra Women's, ICaps Lutein & Omega-3, Tozal, Berocca Plus, PureFe Plus, Vicon Forte, Vitatrum, PureVit DualFe Plus, Daily Multi, Magna-C-7 Forte, Macular Health, Support 500, Centravites 50 Plus, Vica-Forte, Cezin-S, AKEDamins, Eldercaps, Corvita 150, Solo, Senetonic, Caromega, Vita-Min Rx, Advanced Eye Health, Airborne Dual Action, Circavite T, Vitalize Plus, TL G-Fol OS, Airborne Everyday Gummies, Therobec Plus, Airborne Gummies, Zodeac-100, Airborne Kids Gummies, Vitaplex Plus, Airborne Plus Energy, Berplex Plus, Bacmin, Strovite Plus, Becomax Rx, Vicon Plus, Optilets-M-500, Se-Tan Plus, StressTabs with Zinc, Surbex-750 with Zinc, SourceCF Multivitamins with A,B,D,E & K plus Zinc, Vital-D, Alka-Seltzer Plus Immunity Complex, Vitatab MV, SourceCF Softgels, SourceCF Chewables, SourceCF Pediatric Drops, Zinc Plus Lozenges, Centrum Flavor Burst, Centrum Special Immune, Dialyvite 5000, NanoVM, Centrum Silver Women's, Century, One-A-Day Within, One-A-Day Men Pro Edge, Celebrate Multivitamin, Certagen, ProBarimin QT, B-Plex Plus Minerals, Multigenics, Optivite PMT, Bugs Bunny Complete, 50 + Companion, ICaps Plus, Risanoid Plus, ABC to Z, One Tab Daily with Minerals, Diavite Plus, Centrum Special Energy, Centrum Special Heart, One Daily with Minerals, Companion Multi, One-A-Day Max, ConceptionXR MSF, ConceptionXR RHF, Complete Formulation Minis, Century-Vite, One-A-Day Women, Womens Pack, Caltrate 600+D Plus Minerals Minis, Calcet Plus, Gerivite Liquid, Lysiplex Plus, Generix-T, NanoVM 1-3 years, Certagen Senior, NanoVM 4-8 years, Decagen, Geri-Tonic, Avail Calcium Intensive, Vita-Dec, Vigortol Liquid, Centrum Silver Plus Vision, Cerovite Liquid, Cerovite Senior, Myadec, Req49+, Multi-Day with Calcium and Extra Iron, Supervite, Supervite EC, Mens Pack, Magonate Tablets, Citracal Plus Bone Density Builder, Therapeutic-M, T-Lite, Dialyvite Supreme D, Unicap M, Gevratonic, Gold Age Liquid Vitamins and Minerals, Theratrum Complete 50 Plus, Unicap Senior, Garfield Complete Vitamins, Daily Multiple for Men 50+, Complete Formulation Chewables D3000, Z-Gen, Complete Formulation Pediatric Drops, Daily Multiple for Women 50+, Complete Formulation Softgels D3000, Complete Formulation Softgels D5000, Eye Health Formula, TheraCal D2000, Unicap T, TheraCal D4000, Vicon-C, TheraCal Rapid Repletion, Viogen-C, Gynovite, PMS Balance, Procycle Multi Vitamin with Minerals, Dialyvite 800 Ultra D, VP-ZEL, Adeks, Stress 600 with Zinc, Leg-Gesic, Stress Formula with Zinc, Theragener-H, Vi-Zac, Vita-Zinc, Renatabs with Iron, Complete Formulation Chewables, Uni-Thera M with Beta Carotene, T-Gran plus Minerals, Calcium, Magnesium and Zinc, My-A-Multi, Century Senior, Bee-Zee, Compete, Myvitalife, Formula Twenty-One, Mi-C-T, I-Fol Plus, Thera Hematinic, I-Sense, Foli-Iron, ABDEK Pediatric, Eldertonic, Nicadan ZX, Complete Formulation, Unicomplex M, Complete Formulation D3000, Ru-Lets M 500, Complete Formulation D5000, Apatate Forte, Prosight with Lutein, Nu-Iron V, SourceCF ABDEK, L'il Critters Gummy Vites, Daily Combo, Super High Vitamins and Minerals, Corvite Free, Icaps TR, Corvite 150, Centrum Specialist Vision, RE Fac-X, Geritol Extend, Theratrum Complete 50 Plus with Lutein and Lycopene, Theravim M, Companion, Theratrum Complete with Lutein and Lycopene, Beelith, Complete Formulation Softgels, Strovite Forte, elppa Daily, ZE-Plus, Glutofac-ZX, Citracal Plus Magnesium, MaxiVision Eye & Body Formula, Conception XR, Certagen Senior with Lutein, Reocyte Plus, MaxiVision Eye Formula, DermaNIC, L-Tonic, Re Dualvit F, MaxiVision Ocular Formula, Re Dualvit Plus, Glutofac-MX, MaxiVision Whole Body Formula, Nature's Bounty Men's Hair Formula, Embrex 600, Mediplex Ultra, Nutiifac ZX, NicAzel Forte, Formula B Plus, ProCerv HP, M-Vit, Vicap Forte, Vita S Forte, Ocuvite Extra, Protegra Softgel, Centavite, Strovite Advance, Centravites Adults, I-Sense OccuShield, Tab-A-Vite Maximum, DEKAs Bariatric, Uni-Fac ZX, Folgard OS, Dialyvite with Zinc Rx, Dialyvite 800 with Zinc, CF Vite, Strovite Advance+D, Resource Optisource, High Potency, Tab-A-Vite Womens Formula, Astamed MYO, Tab-A-Vite WeightSlim, Dialyvite 3000, Udamin, Udamin SP, Vita Zx, CalciFol, Femtabs, Diatx Zn, Complete A-Z, Thera-Vite M, Nutravance, Ellis Tonic Sherry, Optisource Post Bariatric Surgery, Renax 5.5, O-CAL FA, Men's Hair Formula, Nature's Blend Theratrum Complete Tablets 50 Plus, One-A-Day Mens 50+ Healthy Advantage, Os-Cal Ultra, Puralor Ci with DHA, Opti-Gen, Encora, Star Wars, Disney Winnie the Pooh Complete, Star Wars Hero Gummies, Disney Winnie the Pooh with Extra C, Nutrivit, Star Wars Villain Gummies, Disney Winnie the Pooh Gummies, Star Wars Yoda Gummies, Mag-SR with Calcium, Stress with Zinc, Folpace Rx, NIC 750, CertaVite Senior, ABC Plus Senior, I-Vite Protect, CalciFolic-D, Daily-Vite Weight Control, One-A-Day WeightSmart, Ferrocite Plus, Ecee Plus, Viactiv Multi-Vitamin Flavor Glides, Biotin Forte with Zinc, Folbee Plus CZ, Healthy Eyes, Antioxidant Ultra Formula, Clusimar, Centrum Silver Ultra Men's, Multi-betic, Centrum Ultra Women's, One-A-Day Women 50 Plus, One-A-Day Men 50 Plus, Thera-M Enhanced, Megavite Rx, Centrum Jr with Extra Calcium, Centrum MultiGummies Women, Centrum Vitamints, Recal Fol D)
  • One-A-Day Women (multivitamin with minerals)
  • Pataday (olopatadine ophthalmic)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Meticorten, Sterapred DS, Liquid Pred, Orasone, Prednicen-M)
  • ProAir HFA (albuterol)
  • sucralfate (Carafate)
  • Sudafed Congestion (pseudoephedrine)
  • Symbicort (budesonide / formoterol)
  • Trintellix (vortioxetine)
  • Tums Regular Strength (calcium carbonate)

Actifed Cold and Sinus (acetaminophen / pseudoephedrine / triprolidine) alcohol/food interactions

There is 1 alcohol/food interaction with Actifed Cold and Sinus (acetaminophen / pseudoephedrine / triprolidine)

Actifed Cold and Sinus (acetaminophen / pseudoephedrine / triprolidine) disease interactions

There are 13 disease interactions with Actifed Cold and Sinus (acetaminophen / pseudoephedrine / triprolidine) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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