Zydone Interactions
There are 645 drugs known to interact with Zydone (acetaminophen/hydrocodone), along with 19 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 215 are major, 419 are moderate, and 11 are minor.
- View all 645 medications that may interact with Zydone
- View Zydone alcohol/food interactions (1)
- View Zydone disease interactions (19)
Most frequently checked interactions
View interaction reports for Zydone (acetaminophen / hydrocodone) and the medicines listed below.
- Astelin (azelastine nasal)
- Ativan (lorazepam)
- atropine / diphenoxylate
- Benadryl (diphenhydramine)
- clonazepam
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- DDAVP (desmopressin)
- Desoxyn (methamphetamine)
- docusate
- Fish Oil (omega-3 polyunsaturated fatty acids)
- fluticasone
- furosemide
- hydrochlorothiazide
- ibuprofen
- ipratropium
- meclizine
- melatonin
- Nexium (esomeprazole)
- Percodan (aspirin / oxycodone)
- Remeron (mirtazapine)
- Restasis (cyclosporine ophthalmic)
- Rozerem (ramelteon)
- simvastatin
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vicoprofen (hydrocodone / ibuprofen)
- Zofran (ondansetron)
- zolpidem
Zydone alcohol/food interactions
There is 1 alcohol/food interaction with Zydone (acetaminophen / hydrocodone).
Zydone disease interactions
There are 19 disease interactions with Zydone (acetaminophen / hydrocodone) which include:
- alcoholism
- liver disease
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- PKU
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
More about Zydone (acetaminophen / hydrocodone)
- Zydone consumer information
- Compare alternatives
- Drug images
- Latest FDA alerts (12)
- Side effects
- Dosage information
- During pregnancy
- Drug class: narcotic analgesic combinations
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.