Vicodin HP Interactions
There are 682 drugs known to interact with Vicodin HP (acetaminophen / hydrocodone), along with 19 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 217 are major, 454 are moderate, and 11 are minor.
- View all 682 medications that may interact with Vicodin HP
- View Vicodin HP alcohol/food interactions (1)
- View Vicodin HP disease interactions (19)
Most frequently checked interactions
View interaction reports for Vicodin HP (acetaminophen / hydrocodone) and the medicines listed below.
- Ambien (zolpidem)
- atorvastatin
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- folic acid
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- Lyrica (pregabalin)
- meloxicam
- metformin
- naproxen
- Neurontin (gabapentin)
- omeprazole
- pantoprazole
- prednisone
- Protonix (pantoprazole)
- sertraline
- simvastatin
- tizanidine
- tramadol
- trazodone
- Valium (diazepam)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
Vicodin HP alcohol/food interactions
There is 1 alcohol/food interaction with Vicodin HP (acetaminophen / hydrocodone).
Vicodin HP disease interactions
There are 19 disease interactions with Vicodin HP (acetaminophen / hydrocodone) which include:
- alcoholism
- liver disease
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- PKU
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
Report options
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More about Vicodin HP (acetaminophen / hydrocodone)
- Compare alternatives
- Reviews (10)
- Drug images
- Latest FDA alerts (11)
- Side effects
- Dosage information
- During pregnancy
- Drug class: narcotic analgesic combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
