Norco (acetaminophen / hydrocodone) Drug Interactions
A total of 586 drugs are known to interact with Norco (acetaminophen / hydrocodone).
- 203 major drug interactions
- 373 moderate drug interactions
- 10 minor drug interactions
Check for interactions
Most frequently checked interactions
View interaction reports for Norco (acetaminophen / hydrocodone) and the medicines listed below.
- Ambien (zolpidem)
- amlodipine
- aspirin
- atorvastatin
- baclofen
- cyclobenzaprine
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- ibuprofen
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- metformin
- omeprazole
- prednisone
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Norco (acetaminophen / hydrocodone) alcohol/food interactions
There is 1 alcohol/food interaction with Norco (acetaminophen / hydrocodone)
Norco (acetaminophen / hydrocodone) disease interactions
There are 20 disease interactions with Norco (acetaminophen / hydrocodone) which include:
- alcoholism
- liver disease
- impaired GI motility
- infectious diarrhea
- liver disease
- prematurity
- acute alcohol intoxication
- drug dependence
- gastrointestinal obstruction
- hypotension
- intracranial pressure
- respiratory depression
- PKU
- adrenal insufficiency
- biliary spasm
- hypothyroidism
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
More about Norco (acetaminophen / hydrocodone)
- Side Effects
- During Pregnancy
- Dosage Information
- Patient Tips
- Drug Images
- Compare Alternatives
- Support Group
- Pricing & Coupons
- En Español
- 287 Reviews
- Drug class: narcotic analgesic combinations
- FDA Alerts (11)
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.