Tylenol Cold & Flu Severe Interactions
There are 625 drugs known to interact with Tylenol Cold & Flu Severe (acetaminophen / dextromethorphan / guaifenesin / phenylephrine), along with 7 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 95 are major, 514 are moderate, and 16 are minor.
- View all 625 medications that may interact with Tylenol Cold & Flu Severe
- View Tylenol Cold & Flu Severe alcohol/food interactions (1)
- View Tylenol Cold & Flu Severe disease interactions (7)
Most frequently checked interactions
View interaction reports for Tylenol Cold & Flu Severe (acetaminophen / dextromethorphan / guaifenesin / phenylephrine) and the medicines listed below.
- albuterol
- albuterol
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- benzonatate
- benzonatate
- doxycycline
- doxycycline
- gabapentin
- gabapentin
- ibuprofen
- ibuprofen
- levothyroxine
- levothyroxine
- melatonin
- melatonin
- omeprazole
- omeprazole
- prednisone
- prednisone
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Tylenol Cold & Flu Severe alcohol/food interactions
There is 1 alcohol/food interaction with Tylenol Cold & Flu Severe (acetaminophen / dextromethorphan / guaifenesin / phenylephrine).
Tylenol Cold & Flu Severe disease interactions
There are 7 disease interactions with Tylenol Cold & Flu Severe (acetaminophen / dextromethorphan / guaifenesin / phenylephrine) which include:
Report options
More about Tylenol Cold & Flu Severe (acetaminophen / dextromethorphan / guaifenesin / phenylephrine)
- Compare alternatives
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.