Skip to Content

Valorin Extra (acetaminophen / caffeine) Drug Interactions

A total of 265 drugs are known to interact with Valorin Extra (acetaminophen / caffeine).

  • 32 major drug interactions
  • 98 moderate drug interactions
  • 135 minor drug interactions

Check for interactions with Valorin Extra (acetaminophen / caffeine)

Type in a drug name and select a drug from the list.

Medications known to interact with Valorin Extra (acetaminophen / caffeine)


  • efavirenz (Sustiva)
  • efavirenz / emtricitabine / tenofovir (Atripla)
  • efavirenz / lamivudine / tenofovir (Symfi, Symfi Lo)
  • enoxacin (Penetrex)
  • ephedrine / guaifenesin / theophylline (Primatene Dual Action)
  • ephedrine / hydroxyzine / theophylline (Marax, Hydrophed, Ami-rax, Hydroxy Compound, Marax DF, Theomax DF)
  • ephedrine / phenobarbital / potassium iodide / theophylline (Quadrinal)
  • ephedrine / phenobarbital / theophylline (Tedrigen, Theodrine)
  • epinephrine / prilocaine (Citanest Forte)
  • epirubicin (Ellence, Pharmorubicin PFS, Pharmorubicin RDF)
  • ethanol (Alcohol (contained in alcoholic beverages), Ethyl Alcohol, Dehydrated Alcohol, Alcohol 5% in Dextrose 5%, Alcohol And Dextrose Injections USP Hypertonic, Palcohol, Ablysinol)
  • ethinyl estradiol (Estinyl)
  • ethinyl estradiol / ethynodiol (Kelnor 1/35, Zovia 1/35E, Demulen, Demulen 1/35, Demulen 1/50, Kelnor 1/50, Zovia 1/50E, Malmorede)
  • ethinyl estradiol / etonogestrel (NuvaRing)
  • ethinyl estradiol / folic acid / levonorgestrel (FaLessa Kit)
  • ethinyl estradiol / levonorgestrel (Alesse, Aviane, Levora, Seasonique, Lutera, Aubra, Portia, Vienva, Ashlyna, Lessina, Jolessa, Camrese, Larissia, Kurvelo, Altavera, Levlen, Amethyst, Introvale, Amethia, Daysee, Sronyx, Chateal, Lillow, Falmina, Seasonale, Quasense, Orsythia, Balcoltra, Trivora, Levlite, Triphasil, Marlissa, Quartette, Fayosim, LoSeasonique, Nordette, Amethia Lo, Levonest, Nordette-21, Alesse-28, CamreseLo, Lybrel, Setlakin, Ayuna, Enpresse, Delyla, Aubra EQ, Chateal EQ, Rivelsa, Simpesse, Lo Simpesse, Cerinta, Jaimiess, Afirmelle, Elifemme, Nordette-28, Tri-Levlen, Triphasil-21, Triphasil-28, Alesse-21, Preven EC, Triquilar 21, Triquilar 28, Min-Ovral 21, Min-Ovral 28, Myzilra, Iclevia)
  • ethinyl estradiol / norelgestromin (Xulane, Ortho Evra)
  • ethinyl estradiol / norethindrone (Lo Loestrin Fe, Taytulla, Junel Fe 1/20, Microgestin Fe 1/20, Loestrin 24 Fe, Necon 1/35, Minastrin 24 Fe, Loestrin Fe 1.5/30, Mibelas 24 Fe, Junel Fe 1.5/30, Blisovi Fe 1.5/30, Loestrin 21 1/20, Nortrel 1/35, Jinteli, Microgestin 1.5/30, Blisovi 24 Fe, Blisovi Fe 1/20, Loestrin Fe 1/20, femhrt, Junel 1/20, Larin Fe 1.5/30, Cyclafem 1/35, Estrostep Fe, Balziva, Alyacen 1/35, Larin Fe 1/20, Junel Fe 24, Ortho-Novum 7/7/7, Ortho-Novum 1/35, Tarina Fe 1/20, Microgestin Fe 1.5/30, Fyavolv, Dasetta, Generess Fe, Wera, Wymzya Fe, Brevicon, Norinyl 1+35, Aranelle, Microgestin 1/20, Kaitlib Fe, Gildagia, Philith, Melodetta 24 Fe, Layolis Fe, Pirmella 7/7/7, Pirmella 1/35, Modicon, Cyclafem 7/7/7, Gildess Fe 1/20, Loestrin 21 1.5/30, Necon 0.5/35, Tri-Norinyl, Ovcon 50, Nortrel 7/7/7, Necon 7/7/7, Leena, Junel 1.5/30, Zenchent Fe, Nortrel 0.5/35, Aurovela Fe 1/20, Tri-Legest Fe, Tilia Fe, Lomedia 24 Fe, Dasetta 7/7/7, Dasetta 1/35, Zeosa, Hailey 1.5/30, Microgestin 24 Fe, Vyfemla, Gildess 24 Fe, Larin 24 Fe, Jevantique, Hailey Fe 1/20, Hailey 24 Fe, Ovcon 35, Genora 0.5/35, Nelova 0.5/35, Gildess Fe 1.5/30, Genora 1/35, Norethin 1/35 E, Nelova 10/11, Nelova 1/35, Necon 10/11, Jenest, Ortho-Novum 10/11, Ovcon 35 Fe, Femcon Fe, Nylia 7/7/7, Zenchent, Cyonanz, Nylia 1/35, Aurovela Fe 1.5/30, Aurovela 24 Fe, Aurovela 1/20, Leribane, Aurovela 1.5/30, Cyclafem 0.5/35, Tri-Legest, Lo Minastrin Fe, Briellyn, Hailey Fe 1.5/30, Nexesta Fe, Alyacen 7/7/7, Gildess 1.5/30, Gildess 1/20, Larin 1.5/30, Larin 1/20, Jevantique Lo)
  • ethinyl estradiol / norgestimate (Sprintec, Ortho Tri-Cyclen, TriNessa, Tri-Sprintec, Estarylla, Mononessa, Ortho Cyclen, Ortho Tri-Cyclen Lo, Mono-Linyah, Tri-Lo-Marzia, Previfem, TriNessa Lo, Femynor, Tri-Lo-Sprintec, Tri-Lo-Estarylla, Tri-Linyah, Mili, VyLibra, Tri-Estarylla, Tri-VyLibra, Tri Femynor, Tri-Previfem, Tri-Lo-Mili, Tri-Mili)
  • ethinyl estradiol / norgestrel (Cryselle, Lo/Ovral, Low-Ogestrel-28, Ovral, Lo/Ovral-28, Ovral-21, Elinest, Ogestrel 0.5/50, Ovral-28)
  • ethinyl estradiol / segesterone (Annovera)
  • ethotoin (Peganone)
  • ramelteon (Rozerem)
  • ranitidine (Zantac, Zantac 150, Zantac 75, Zantac 300, Deprizine, Zantac Injection, Acid Reducer, Zantac 150 EFFERdose, Taladine, Zantac 25 mg EFFERdose, Berkley and Jensen Acid Reducer Maximum Strength, Zantac GELdose, Zantac 300 GELdose, Zantac EFFERdose, Acid Reducer Non-Prescription Strength, Acid Relief, Sunmark Acid Reducer Maximum Strength, Acid Control 75, Careone Acid Reducer, Equaline Heartburn Relief, Acid Control 150)
  • ranitidine bismuth citrate (Tritec)
  • rasagiline (Azilect)
  • regadenoson (Lexiscan)
  • rifampin (Rifadin, Rimactane, Rifadin IV)
  • riluzole (Rilutek, Tiglutik)
  • ropinirole (Requip, Requip XL, ReQuip Starter Pack, ReQuip Follow on Pack, Repreve, Requip Starter Kit)
  • ropivacaine (Naropin, Naropin SDV, Naropin Polyamp, Naropin Novaplus)
  • ropivacaine / sufentanil
  • rucaparib (Rubraca)
  • terbinafine (Lamisil, Terbinex)
  • teriflunomide (Aubagio)
  • theophylline (Theo-Dur, Theo-24, Theolair, Uniphyl, Theochron, Truxophyllin, Quibron-T, Elixophyllin, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theovent, Bronkodyl, Theo-X, Theo-Time, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T/SR, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Asmalix, Aquaphyllin, Constant-T, TheoCap, Slo-Phyllin 250)
  • thiabendazole (Mintezol)
  • thioguanine (Tabloid)
  • thiopental (Pentothal)
  • tizanidine (Zanaflex)
  • tolterodine (Detrol, Detrol LA)
  • topotecan (Hycamtin)
  • trabectedin (Yondelis)
  • trihexyphenidyl (Artane, Trihexane, Trihexy)
  • trospium (Sanctura, Regurin, Sanctura XR)
  • trovafloxacin (Trovan)

Valorin Extra (acetaminophen / caffeine) alcohol/food interactions

There are 6 alcohol/food interactions with Valorin Extra (acetaminophen / caffeine)

Valorin Extra (acetaminophen / caffeine) disease interactions

There are 12 disease interactions with Valorin Extra (acetaminophen / caffeine) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.