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VEGF/VEGFR inhibitors

What are VEGF/VEGFR inhibitors?

Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are agents that inhibit the activity of VEGF and VEGFR. VEGR and VEGFR (a tyrosine kinase receptor) signaling modulates angiogenesis, which involves making of new blood vessels from existing blood vessels.

Abnormal angiogenesis is known to occur in cancer, degenerative eye conditions and other conditions that involve inflammation. Specific monoclonal antibodies can be used as VEGF inhibitors and particular tyrosine kinase inhibitors are used as VEGFR inhibitors.

Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are used to treat various types of cancers.

List of VEGF/VEGFR inhibitors:

View by  Brand | Generic
Drug Name Reviews Avg. Ratings
Avastin (Pro)
Generic name: bevacizumab
25 reviews
8.0
Cabometyx (Pro)
Generic name: cabozantinib
5 reviews
8.6
Caprelsa (Pro)
Generic name: vandetanib
0 reviewsAdd rating
Cometriq (Pro)
Generic name: cabozantinib
2 reviews
1.0
Cyramza (Pro)
Generic name: ramucirumab
0 reviewsAdd rating
Iclusig (Pro)
Generic name: ponatinib
2 reviews
3.0
Inlyta (Pro)
Generic name: axitinib
0 reviews
6.0
Lenvima (Pro)
Generic name: lenvatinib
2 reviews
7.5
Mvasi (Pro)
Generic name: bevacizumab
0 reviewsAdd rating
Nexavar (Pro)
Generic name: sorafenib
14 reviews
5.4
Stivarga (Pro)
Generic name: regorafenib
4 reviews
4.0
Sutent (Pro)
Generic name: sunitinib
28 reviews
7.0
Votrient (Pro)
Generic name: pazopanib
75 reviews
8.2
Zaltrap (Pro)
Generic name: ziv-aflibercept
1 review
10
Zirabev (Pro)
Generic name: bevacizumab
0 reviewsAdd rating
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.