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Selective serotonin reuptake inhibitors

Other names: SSRIs

What are Selective serotonin reuptake inhibitors

Selective serotonin reuptake inhibitors (also called SSRIs) are medicines that increase the levels of a chemical messenger in the brain called serotonin. An imbalance of serotonin in the brain is thought to contribute to depression, anxiety, poor mood, sexual dysfunction, OCD and stress. SSRIs act to regulate the serotonin levels.

How they work

SSRIs work to increase serotonin which is a chemical messenger. The nerves in the brain communicate with each other by one nerve releasing serotonin and the next nerve absorbing the serotonin. Any extra serotonin that is left over is taken up by the nerve that released it which lowers the amount of serotonin available. The SSRIs stop the original nerve from “reuptaking” the serotonin so that there is more serotonin available for the second nerve to absorb. In depression and other related disorders by increasing the serotonin between the nerve endings results in messages being able to be sent more effectively. The full therapeutic effect of taking SSRIs may take several weeks or longer to become noticeable.

What they treat

SSRIs are used in the treatment of depression and other mood disorders, eating disorders, panic disorder, obsessive compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD) and anxiety.

Side effects

SSRIs may cause some side effects which can depend on which type of SSRIs has been taken. Side effects may include agitation, blurred vision, dizziness, drowsiness, dry mouth, headache, insomnia, sexual problems, nausea, diarrhea or upset stomach. In some age groups there maybe an increase in suicidal thoughts and behaviour.

List of Selective serotonin reuptake inhibitors:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
escitalopram systemic (Pro, More...)
1,924 reviews
citalopram systemic (Pro, More...)
1,437 reviews
fluoxetine systemic (Pro, More...)
1,114 reviews
sertraline systemic (Pro, More...)
2,088 reviews
paroxetine systemic (Pro, More...)
935 reviews
fluvoxamine systemic (Pro, More...)
172 reviews