Timothy Grass Pollen Allergen Extract Dosage

Usual Adult Dose for Allergic Rhinitis

One tablet sublingually once a day

Comments:
-Initiate treatment at least 12 weeks before the expected onset of each grass pollen season and continue treatment throughout the season.

Use: Treatment of grass pollen-induced allergic rhinitis with or without conjunctivitis confirmed by positive skin test or in vitro testing for pollen-specific IgE antibodies for timothy grass or cross-reactive grass pollens.

Usual Pediatric Dose for Allergic Rhinitis

One tablet sublingually once a day

Comments:
-Initiate treatment at least 12 weeks before the expected onset of each grass pollen season and continue treatment throughout the season.
-Administer to children under adult supervision.

Use: Treatment of grass pollen-induced allergic rhinitis with or without conjunctivitis confirmed by positive skin test or in vitro testing for pollen-specific IgE antibodies for timothy grass or cross-reactive grass pollens.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

US BOXED WARNING:
-Timothy grass allergen extract can cause life-threatening allergic reactions such as anaphylaxis and severe laryngopharyngeal restriction.
-Do not administer to patients with severe, unstable or uncontrolled asthma.
-Observe patients in the office for at least 30 minutes following the initial dose.
-Prescribe auto-injectable epinephrine, instruct and train patients on its appropriate use, and instruct patients to seek immediate medical care upon its use.
-May not be suitable for patients with certain underlying medical conditions that may reduce their ability to survive a serious allergic reaction.
-May not be suitable for patients who may be unresponsive to epinephrine or inhaled bronchodilators, such as those taking beta-blockers.

Safety and efficacy have not been established in patients younger than 5 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-For sublingual use only.
-Administer the first dose in a healthcare setting under the supervision of a physician with experience in the field.
-After receiving the first dose, observe the patient for at least 30 minutes to monitor for signs or symptoms of a severe systemic or a severe local allergic reaction.
-Administer to children under adult supervision.
-Allow the tablet to remain under the tongue until completely dissolved. Do not swallow for at least 1 minute.
-Wash hands after handling the tablet.
-Do not take the tablet with food or beverage. Food or beverage should not be taken for at least 5 minutes after taking the tablet.
-Prescribe auto-injectable epinephrine to patients and instruct them in the proper use of emergency self-injection of epinephrine.

Storage requirements:
-Protect from moisture