Rezvoglar Kwikpen Dosage
Generic name: Insulin glargine 100[iU] in 1mL
Dosage form: injection, solution
Drug class: Insulin
Medically reviewed by Drugs.com. Last updated on Nov 16, 2022.
Important Administration Instructions
- Always check insulin labels before administration [see Warnings and Precautions (5.4)].
- Visually inspect REZVOGLAR KwikPen prefilled pens for particulate matter and discoloration prior to administration. Only use if the solution is clear and colorless with no visible particles.
- Administer REZVOGLAR subcutaneously into the abdominal area, thigh, or deltoid, and rotate injection sites within the same region from one injection to the next to reduce the risk of lipodystrophy and localized cutaneous amyloidosis. Do not inject into areas of lipodystrophy or localized cutaneous amyloidosis [see Warnings and Precautions (5.2), and Adverse Reactions (6)].
- During changes to a patient's insulin regimen, increase the frequency of blood glucose monitoring [see Warnings and Precautions (5.2)].
- Do not administer intravenously or via an insulin pump.
- Do not dilute or mix REZVOGLAR with any other insulin or solution.
- The REZVOGLAR KwikPen prefilled pen dials in 1-unit increments.
- Use REZVOGLAR KwikPen prefilled pen with caution in patients with visual impairment who may rely on audible clicks to dial their dose.
General Dosing Instructions
- Administer REZVOGLAR subcutaneously once daily at any time of day but at the same time every day.
- Individualize and adjust the dosage of REZVOGLAR based on the patient's metabolic needs, blood glucose monitoring results and glycemic control goal.
- Dosage adjustments may be needed with changes in physical activity, changes in meal patterns (i.e., macronutrient content or timing of food intake), during acute illness, or changes in renal or hepatic function. Dosage adjustments should only be made under medical supervision with appropriate glucose monitoring [see Warnings and Precautions (5.2)].
- In patients with type 1 diabetes, REZVOGLAR must be used concomitantly with short-acting insulin.
Initiation of REZVOGLAR Therapy
Recommended Starting Dosage in Patients with Type 1 Diabetes
The recommended starting dosage of REZVOGLAR in patients with type 1 diabetes is approximately one-third of the total daily insulin requirements. Use short-acting, premeal insulin to satisfy the remainder of the daily insulin requirements.
Recommended Starting Dosage in Patients with Type 2 Diabetes
The recommended starting dosage of REZVOGLAR in patients with type 2 diabetes who are not currently treated with insulin is 0.2 units/kg or up to 10 units once daily.
Switching to REZVOGLAR from Other Insulin Therapies
Dosage adjustments are recommended to lower the risk of hypoglycemia when switching patients to REZVOGLAR from other insulin therapies [see Warnings and Precautions (5.3)]. When switching from:
- Once-daily insulin glargine, 300 units/mL, to once-daily REZVOGLAR (100 units/mL), the recommended starting REZVOGLAR dosage is 80% of the insulin glargine, 300 units/mL dosage that is being discontinued.
- Once-daily NPH insulin to once-daily REZVOGLAR, the recommended starting REZVOGLAR dosage is the same as the dosage of NPH that is being discontinued.
- Twice-daily NPH insulin to once-daily REZVOGLAR, the recommended starting REZVOGLAR dosage is 80% of the total NPH dosage that is being discontinued.
Frequently asked questions
- What are biosimilar drugs?
- How many biosimilars have been approved in the United States?
- What are the different types of insulin?
- How and where should I inject insulin?
- Toujeo vs Tresiba - What's the difference between them?
- Is Tresiba the same as Lantus?
- When is the best time to take Toujeo?
- How long can Toujeo stay out of the refrigerator?
- How much Toujeo is too much?
- Soliqua vs Lantus: What’s the difference between them?
- Does Lantus cause weight gain?
- Can Toujeo be given twice a day?
- How many pens are in a box of Toujeo?
- What is the difference between Soliqua and Xultophy?
- Is Toujeo a fast or long-acting insulin?
More about Rezvoglar (insulin glargine)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Latest FDA alerts (3)
- Side effects
- During pregnancy
- Drug class: insulin
Lantus, Basaglar, Toujeo, Lantus SoloStar, ... +2 more
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.