Radium 223 Dichloride Dosage
Medically reviewed by Drugs.com. Last updated on March 17, 2020.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Prostate Cancer
50 kilobecquerel (kBq) or 1.35 microcurie per kg body weight, IV, every 4 weeks
Duration of therapy: 6 doses
Comments: See manufacturer's product information for complete dosing instructions including decay correction factor table and calculation of correct volume for dosing.
Use: The treatment of patients with castration-resistant prostate cancer, symptomatic bone metastases, and no known visceral metastatic disease.
Renal Dose Adjustments
Mild to moderate renal impairment (CrCl 30 to 89 mL/min): No adjustment recommended
Severe renal impairment (CrCl less than 30 mL/min): Data not available
Liver Dose Adjustments
Mild hepatic impairment: No adjustment recommended
Moderate to severe hepatic impairment: Data not available
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for dosing related precautions.
Data not available
Administration advice: Administer by slow intravenous injection over 1 minute.
Storage requirements: Store in the original container or equivalent radiation shielding.
Reconstitution/preparation techniques: The manufacturer's product information should be consulted.
-Follow procedures for proper handling and disposal of radioactive pharmaceuticals.
-This preparation is approved for use only by persons under license by the Nuclear Regulatory Commission or the relevant regulatory authority of an Agreement State.
More about radium 223 dichloride
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- Drug class: therapeutic radiopharmaceuticals
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