Penbutolol Dosage
Applies to the following strengths: 20 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Angina Pectoris Prophylaxis
Initial dose: 20 mg orally once a day.
Maintenance dose: 20 to 40 mg orally once a day.
Usual Adult Dose for Hypertension
Initial dose: 20 mg orally once a day.
Maintenance dose: 20 to 40 mg orally once a day.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Initial dose: 10 mg orally once a day.
Maintenance dose: Dose increments should be made cautiously.
Precautions
If penbutolol is discontinued, consider gradual reduction of dose to avoid rebound hypertension or angina pectoris.
Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).
Dialysis
Data not available
Other Comments
The full effect of a dose may not be observed for 4 to 6 weeks. The maximum daily recommended dose is 80 mg.
Compared with Caucasian patients, Black patients have a reduced blood pressure response to monotherapy with beta blockers; however, the reduced response is largely eliminated if combination therapy that includes an adequate dose of a diuretic is instituted.
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- During pregnancy
- Drug class: non-cardioselective beta blockers
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