Eprosartan Dosage

Usual Adult Dose for Hypertension

Initial dose: 600 mg orally once a day as monotherapy assuming euvolemia
Maintenance dose: 400 to 800 mg orally per day in 1 or 2 divided doses

Comments:

• Maximum blood pressure reduction may take 2 to 3 weeks.
• If antihypertension measured at trough using once a day dosing is inadequate, consider twice a day dosing at the same daily dose or an increased dose.
• Limited experience exists with daily doses greater than 800 mg.

Renal Dose Adjustments

Mild renal dysfunction: No initial adjustment recommended
Moderate to severe renal dysfunction: No initial adjustment recommended; maximum dose: 600 mg/day

Liver Dose Adjustments

No initial adjustment recommended

Precautions

US BOXED WARNING:

• FETAL TOXICITY: If pregnancy is detected, discontinue this drug as soon as possible. Drugs that act directly on the renin angiotensin system (RAS) can cause injury and death to the developing fetus.

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Monitoring: Assess renal function prior to therapy and periodically thereafter.

Patient advice: Females of childbearing age should be informed of the consequences of exposure to this drug during pregnancy; ask these patients to report pregnancies as soon as possible.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer