Dorzolamide / Timolol Ophthalmic Dosage
Medically reviewed by Drugs.com. Last updated on Apr 23, 2025.
Applies to the following strengths: 2.23%-0.68% (2%-0.5% base); 2.23%-0.68% (2%-0.5% base) preservative-free
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Intraocular Hypertension
1 drop in the affected eye(s) 2 times per day
Comments:
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart.
- The solution from one individual unit is to be used immediately after opening for administration to one or both eyes.
- The remaining contents should be discarded immediately after administration.
Use: To reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time)
Usual Adult Dose for Glaucoma (Open Angle)
1 drop in the affected eye(s) 2 times per day
Comments:
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart.
- The solution from one individual unit is to be used immediately after opening for administration to one or both eyes.
- The remaining contents should be discarded immediately after administration.
Use: To reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time)
Usual Pediatric Dose for Intraocular Hypertension
2 years or older:
1 drop in the affected eye(s) 2 times per day
Comments:
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart.
- The solution from one individual unit is to be used immediately after opening for administration to one or both eyes.
- The remaining contents should be discarded immediately after administration.
Use: To reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time)
Usual Pediatric Dose for Glaucoma (Open Angle)
2 years or older:
1 drop in the affected eye(s) 2 times per day
Comments:
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart.
- The solution from one individual unit is to be used immediately after opening for administration to one or both eyes.
- The remaining contents should be discarded immediately after administration.
Use: To reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time)
Renal Dose Adjustments
Mild to moderate renal impairment: Data not available
Severe renal impairment (CrCl less than 30 mL/min): Not recommended
Liver Dose Adjustments
Hepatic impairment: Use with caution
Precautions
Safety and efficacy have not been established in patients younger than 2 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Patient advice:
- Patients should be instructed to wash their hands before use and avoid allowing the tip of the container to come into contact with the eye or surrounding structures.
Storage requirements:
- Protect from light.
- Do not freeze.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.