Aspirin / Butalbital / Caffeine / Codeine Dosage
Applies to the following strength(s): 325 mg-50 mg-40 mg-30 mg
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Headache
1 or 2 capsules orally every 4 hours as needed not to exceed 6 capsules per day
-Due to high rate of physical dependence, the extended use of this drug is not recommended.
-The safety and efficacy of treating multiple recurrent headaches with this product is not known.
Uses: For the relief of the symptom complex of tension (or muscle contraction) headache.
Renal Dose Adjustments
Use with caution
Liver Dose Adjustments
Use with caution
Elderly: Dose selection should be cautious, usually starting at the low end of the dose range.
The drug should not be abruptly discontinued in the physically dependent person.
US BOXED WARNING: DEATH RELATED TO ULTRA-RAPID METABOLISM OF CODEINE TO MORPHINE
-Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being an ultra-rapid metabolizer of codeine due to a CYP2D6 polymorphism.
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
US Controlled Substance: Schedule III
Data not available
-Take orally as needed
-Do not exceed 6 capsules per day
Storage requirements: Protect from light and moisture
-Butalbital and codeine are drugs that may be abused; extended use is not recommended.
-Monitor for potential abuse
-Monitor for respiratory depression and signs of morphine overdose
-Monitor liver function tests in patients with severe hepatic disease
-Monitor renal function tests in patients with severe renal disease
-Patients should be advised that this drug has the potential to cause physical and psychological dependence, and tolerance; patients should be instructed to take this drug as prescribed, in the amounts prescribed, and no more frequently than prescribed.
-Patients should understand the risks of life-threatening respiratory depression and when this risk is greatest, patients should be aware that a genetic mutation may result in greater toxicity in some patients.
-Patients should understand that this drug contains aspirin and should not be taken by patients with an allergy or sensitivity to aspirin.
-Patients should be advised to avoid alcohol and performance of potentially hazardous tasks (such as driving a car) while taking this drug.
-Women of childbearing potential should be advised to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
More about aspirin/butalbital/caffeine/codeine
- Aspirin, butalbital, caffeine, and codeine
- Butalbital, aspirin, caffeine, and codeine (Advanced Reading)
- Butalbital,Aspirin,Caffeine,Codeine (FDA)
- Butalbital, Aspirin, Caffeine, and Codeine (Wolters Kluwer)