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Ziconotide Disease Interactions

There are 2 disease interactions with ziconotide:


Ziconotide (Includes ziconotide) ↔ infection

Major Potential Hazard, Moderate plausibility. Applies to: Infection - Bacterial/Fungal/Protozoal/Viral, Bleeding

The use of ziconotide is contraindicated in patients with any other concomitant treatment or medical condition that would render intrathecal administration hazardous. Contraindications to the use of intrathecal analgesia include the presence of infection at the microinfusion injection site, uncontrolled bleeding diathesis, and spinal canal obstruction that impairs circulation of cerebrospinal fluid.


Ziconotide (Includes ziconotide) ↔ psychosis

Major Potential Hazard, Moderate plausibility. Applies to: Psychosis

The use of ziconotide is contraindicated in patients with a preexisting history of psychosis. Severe psychiatric symptoms and neurological impairment may occur during therapy with ziconotide. It is recommended to monitor all patients for evidence of cognitive impairment, hallucinations, or changes in mood or consciousness during treatment with ziconotide. Discontinue therapy with ziconotide in the event of serious neurological or psychiatric signs or symptoms.

Ziconotide drug interactions

There are 231 drug interactions with ziconotide

Ziconotide alcohol/food interactions

There is 1 alcohol/food interaction with ziconotide

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.