Ticon Disease Interactions
There are 3 disease interactions with Ticon (trimethobenzamide).
Trimethobenzamide (applies to Ticon) Reye's syndrome
Major Potential Hazard, High plausibility.
The use of trimethobenzamide should be avoided in children and adolescents whose signs and symptoms suggest Reye's syndrome. The extrapyramidal symptoms which can occur secondary to trimethobenzamide use may confound the diagnosis of Reye's syndrome. In addition, drugs with hepatotoxic potential such as trimethobenzamide may adversely affect the course of Reye's syndrome.
Trimethobenzamide (applies to Ticon) parkinsonism
Moderate Potential Hazard, High plausibility.
The use of trimethobenzamide has been associated with pseudo- parkinsonian reactions including mask- like faces, drooling, cogwheel rigidity, and shuffling gait. Therapy with trimethobenzamide should be administered cautiously in patients with parkinsonism.
Trimethobenzamide (applies to Ticon) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Trimethobenzamide is mostly eliminated by the kidneys and a dosage adjustment should be considered in patients with reduced renal function (creatinine clearance <= 70 mL/min), including some elderly patients.
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Ticon drug interactions
There are 240 drug interactions with Ticon (trimethobenzamide).
Ticon alcohol/food interactions
There is 1 alcohol/food interaction with Ticon (trimethobenzamide).
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- Drug class: anticholinergic antiemetics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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