Purelax (polyethylene glycol 3350) Disease Interactions
There is 1 disease interaction with Purelax (polyethylene glycol 3350):
Peg Solutions (Includes Purelax) ↔ Gi Obstruction/Perforation
Severe Potential Hazard, Moderate plausibility
Applies to: Gastrointestinal Obstruction, Gastrointestinal Perforation, Ulcerative Colitis
The use of polyethylene glycol (PEG) solutions is contraindicated in patients with gastrointestinal obstruction, perforation, or toxic megacolon. If gastrointestinal obstruction or perforation is suspected, appropriate studies should be performed prior to administration of these agents. Use with caution in patients with severe active ulcerative colitis. Increased activity of the gut caused by these agents could worsen these conditions.
- Raymond PL "Mallory-Weiss tear associated with polyethylene glycol electrolyte lavage solution." Gastrointest Endosc 37 (1991): 410-1
- "Product Information. Golytely (polyethylene glycol electrolyte solution)." Braintree, Braintree, MA.
- McBride MA, Vanagunas A "Esophageal perforation associated with polyethylene glycol electrolyte lavage solution." Gastrointest Endosc 39 (1993): 856-7
Purelax (polyethylene glycol 3350) drug Interactions
There are 231 drug interactions with Purelax (polyethylene glycol 3350)
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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